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Fetal Disorders

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What is the most common cause of fetal anemia?

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a. Alpha thalassemia

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b. Fetomaternal hemorrhage

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c. Parvovirus B19 infection

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d. Red cell alloimmunization

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What is the approximate prevalence of red cell alloimmunization in pregnancy?

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a. 0.1%

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b. 1%

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c. 5%

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d. 8%

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Most cases of severe fetal anemia secondary to alloimmunization are due to all EXCEPT which of the following antibodies?

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a. Anti-c

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b. Anti-d

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c. Anti-D

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d. Anti-Kell

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What is the critical titer for anti-D antibody alloimmunization?

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a. 1:4

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b. 1:8

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c. 1:16

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d. 1:32

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What is the minimum amount of fetal erythrocytes needed in the maternal circulation to provoke sensitization to D antigen?

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a. 0.01 mL

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b. 0.1 mL

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c. 1 mL

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d. 5 mL

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A mother whose blood type is A negative labors and delivers a B-positive child at term. She does not receive anti-D immune globulin postpartum. What are the chances that the patient will become alloimmunized?

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a. 2%

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b. 8%

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c. 20%

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d. 33%

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All EXCEPT which of the following antibodies are harmless in pregnancy?

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a. Anti-I

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b. Anti-Lua

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c. Anti-Fyb

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d. Anti-Lewis

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