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Thromboembolic Disorders

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What is the approximate incidence of thromboembolic events per pregnancy?

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a. 1/10

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b. 1/100

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c. 1/1000

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d. 1/10,000

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Which of the following statements is correct regarding the timing of pregnancy-related deep-vein thrombosis (DVT) and pulmonary embolism (PE)?

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a. DVT and PE are more common antepartum.

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b. DVT and PE are more common postpartum.

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c. DVT is more common antepartum, and PE is more common postpartum.

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d. PE is more common antepartum, and DVT is more common postpartum.

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All EXCEPT which of the following physiologic alterations predispose to venous thrombosis in pregnancy?

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a. Lower extremity venous stasis

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b. Decreased plasminogen activity

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c. Endothelial cell injury at delivery

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d. Increased synthesis of clotting factors

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Which of the following risk factors for developing thromboembolism in pregnancy is most important?

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a. Cesarean delivery

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b. Multifetal gestation

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c. Postpartum hemorrhage

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d. Personal history of thrombosis

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Approximately what percentage of thromboembolic events that occur during pregnancy can be attributed to an inherited or acquired thrombophilia?

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a. 1%

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b. 15%

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c. 50%

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d. 75%

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The mutations that cause antithrombin deficiency are almost always inherited in what fashion?

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a. X-linked dominant

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b. X-linked recessive

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c. Autosomal dominant

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d. Autosomal recessive

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Understanding pregnancy physiology is essential to diagnose protein S deficiency. Concentrations of which of the following decline substantially during normal pregnancy?

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