Skip to Main Content

++

Hepatic, Biliary, and Pancreatic Disorders

++
++
++

All EXCEPT which of the following liver-related changes are physiologic in pregnancy?

++
++
++

a. Asterixis

++
++

b. Palmar erythema

++
++

c. Spider angiomas

++
++

d. Elevated serum alkaline phosphatase levels

++
++ ++
++
++

What is the underlying pathophysiology of intrahepatic cholestasis of pregnancy?

++
++
++

a. Acute hepatocellular destruction

++
++

b. Incomplete clearance of bile acids

++
++

c. Microvascular thrombus accumulation

++
++

d. Eosinophil infiltration of the liver

++
++ ++
++
++

Which of the following clinical features are characteristic of intrahepatic cholestasis of pregnancy?

++
++
++

a. Maculopapular rash

++
++

b. Nausea and vomiting

++
++

c. Generalized pruritis

++
++

d. Serum transaminase levels > 500 U/L

++
++ ++
++
++

Which of the following viral infections has been associated with a marked increase in the risk for intrahepatic cholestasis of pregnancy?

++
++
++

a. Hepatitis C

++
++

b. Hepatitis B

++
++

c. Cytomegalovirus

++
++

d. Human immunodeficiency virus

++
++ ++
++
++

A 42-year-old primigravida presents at 35 weeks’ gestation with several new complaints. Most bothersome is yellowing of her sclera. After performing a thorough history, physical, and laboratory evaluation, you make a diagnosis of intrahepatic cholestasis of pregnancy. Approximately what percentage of women with this condition will develop jaundice?

++
++
++

a. < 1%

++
++

b. 10%

++
++

c. 50%

++
++

d. > 90%

++
++ ++
++
++

A 42-year-old primigravida presents at 35 weeks’ gestation with several new complaints. Most bothersome is yellowing of her sclera. After performing a thorough history, physical, and laboratory evaluation, you make a diagnosis of intrahepatic cholestasis of pregnancy. Referring to the patient, which of the following medications is most appropriate to initiate?

++
++
++

a. Hydroxyzine

++
...

Pop-up div Successfully Displayed

This div only appears when the trigger link is hovered over. Otherwise it is hidden from view.