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Hematological Disorders

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A hemoglobin concentration below which of the following thresholds would indicate anemia in an iron-supplemented pregnant woman in any trimester?

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a. 9.0 g/dL

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b. 9.5 g/dL

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c. 10.0 g/dL

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d. 10.5 g/dL

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What is the most common cause of antepartum anemia in pregnant women?

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a. Thalassemia

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b. Iron deficiency

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c. Folic acid deficiency

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d. Anemia of chronic disease

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A 19-year-old primigravida at 29 weeks’ gestation is noted to have anemia with a hemoglobin concentration of 8 g/dL. The peripheral blood smear below is obtained. Which of the following laboratory findings are likely to accompany this condition?

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Reproduced with permission from Beutler E: Disorders of iron metabolism. In Lichtman MA, Kipps TJ, Seligsohn U (eds): Williams Hematology, 8th ed. New York, McGraw-Hill, 2010, Figure 42-10C.

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a. Decreased serum ferritin level

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b. Elevated mean corpuscular volume

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c. Decreased total iron binding capacity

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d. Positive sickle-cell screen (Sickledex) result

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A 19-year-old primigravida at 29 weeks’ gestation is noted to have anemia with a hemoglobin concentration of 8 g/dL. The peripheral blood smear below is obtained. For the patient, what is the most appropriate initial treatment?

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Reproduced with permission from Beutler E: Disorders of iron metabolism. In Lichtman MA, Kipps TJ, Seligsohn U (eds): Williams Hematology, 8th ed. New York, McGraw-Hill, 2010, Figure 42-10C.

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a. Red cell transfusion

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b. Folic acid, 4 mg orally daily

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c. Hydroxyurea, 1 g orally daily

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d. Elemental iron, 200 mg orally daily

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Of medical conditions associated with anemia of chronic disease, which is most frequently encountered in pregnancy?

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a. Crohn disease

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