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Polycystic Ovarian Syndrome and Hyperandrogenism

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Which of the following criteria for diagnosis of polycystic ovarian syndrome (PCOS) is not part of the Rotterdam criteria?

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a. Oligo-/anovulation

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b. Sonographic polycystic appearance of ovaries

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c. Clinical or biochemical signs of hyperandrogenism

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d. Peripheral distribution of follicles on sonography

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In ovarian hyperthecosis, which of the following is LEAST likely to be seen?

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a. Irregular menstrual cycles

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b. Physical signs of hyperandrogenism

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c. Biochemical evidence of hyperandrogenism

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d. More than 12 follicles per ovary during sonography

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First-degree male relatives of women with PCOS have been shown to have higher levels of which of the following circulating hormones?

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a. Testosterone

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b. Androstenedione

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c. Dihydrotestosterone

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d. Dehydroepiandrosterone sulfate

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In PCOS, increased testosterone production from the ovaries is secondary to stimulation by which of the following hormones?

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a. Inhibin

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b. Estradiol

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c. Luteinizing hormone (LH)

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d. Follicle-stimulating hormone (FSH)

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All EXCEPT which of the following hormones are increased in women with PCOS?

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a. Luteinizing hormone (LH)

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b. Follicle-stimulating hormone (FSH)

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c. Estradiol

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d. Testosterone

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All EXCEPT which of the following are true regarding sex hormone-binding globulin (SHBG)?

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a. It is a product of the liver.

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b. Levels are increased by insulin.

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c. Levels are increased by estradiol.

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d. It binds most of the circulating testosterone.

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Which of the following is NOT typical of ...

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