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Pediatric Gynecology

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Which of the following statements is FALSE regarding the development of the hypothalamic–pituitary-ovarian axis in the female fetus and neonate?

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a. By 5 months’ gestation, 6 to 7 million oocytes have been created from accelerated germ cell division.

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b. The gonadotropin-releasing hormone (GnRH) “pulse generator” remains functionally dormant until several months after birth.

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c. At birth, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) concentrations rise and remain high during the first 3 months of life.

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d. Neonatal breast budding, minor uterine bleeding, and transient ovarian cysts may occur as a normal response to initially high gonadotropin levels.

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Which of the following statements is true regarding pelvic anatomy in the female infant and child?

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a. The ovaries have obtained their normal adult size by birth.

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b. At birth, the uterus and cervix are approximately equal in size.

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c. Presence of an endometrial stripe or fluid within the endometrial cavity of the newborn uterus is a normal finding with sonography.

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d. All the above are true statements.

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Which of the following generally occurs first among the major developmental events of female puberty?

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a. Menarche

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b. Pubarche

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c. Thelarche

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d. Growth spurt

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An alarmed parent brings her 8-year-old daughter in for evaluation of breast budding. The child shows no other signs of puberty. Precocious puberty is defined as initial pubertal changes occurring prior to what threshold age?

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a. 6 years

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b. 7 years

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c. 8 years

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d. 9 years

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Delayed puberty is characterized by a lack of initial pubertal changes, usually thelarche, by what threshold age?

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a. 13 years

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b. 14 years

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c. 15 years

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d. 16 years

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