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Reproductive Endocrinology

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Which of the following most accurately describes autocrine hormone communication?

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a. A cell secretes a hormone that acts on a neighboring cell.

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b. A cell secretes a hormone that influences its own function.

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c. The hormone is secreted and acts upon a distant target tissue.

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d. The hormone produced acts within the cell before it is secreted.

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The figure below portrays which type of hormone action?

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Reproduced with permission from Hoffman BL, Schorge JO, Bradshaw KD, et al: Williams Gynecology, 3rd ed. New York, McGraw-Hill, 2016. Figure 15-1B.

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a. Autocrine

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b. Endocrine

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c. Paracrine

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d. Intracrine

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Which of the following statements is true regarding the gonadotropin luteinizing hormone (LH)?

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a. It is secreted by the posterior pituitary gland.

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b. Its functional specificity is derived from the α-subunit.

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c. It shares a common glycoprotein β-subunit with follicle-stimulating hormone (FSH).

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d. Its β-subunit demonstrates approximately 80 percent homology with that of human chorionic gonadotropin (hCG).

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A 48-year-old woman presents to the Emergency Department with severe upper abdominal pain and a positive pregnancy test. She has had a prior tubal ligation. A computed tomography scan performed to evaluate her pain is significant for multiple heterogeneous hepatic lesions (shown below). Her serum β-human chorionic gonadotropin (β-hCG) test result is 115 mIU/mL. Transvaginal sonography results are also shown below. Chest radiographs are normal. What is the most likely source of her hCG?

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a. Liver tumors

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b. Exogenous hCG injection

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c. Partial molar pregnancy

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d. Complete molar pregnancy

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Which of the following statements regarding steroidogenesis is FALSE?

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