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Epithelial Ovarian Cancer

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In what place is ovarian cancer currently ranked among causes of cancer-related death in US women?

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a. First

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b. Fifth

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c. Tenth

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d. Fifteenth

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What percentage of epithelial ovarian cancers is hereditary?

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a. 0.01 percent

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b. 0.3 percent

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c. 10 percent

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d. 30 percent

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Which of the following is NOT a risk factor for ovarian cancer?

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a. Nulliparity

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b. Late menopause

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c. Oral contraceptive pills

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d. Hereditary nonpolyposis colorectal cancer

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Which of the following genetic mutations is associated with the highest risk of developing ovarian cancer?

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a. PTEN

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b. MLH1

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c. BRCA1

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d. BRCA2

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Which of the following statements regarding BRCA variants of uncertain clinical significance is FALSE?

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a. Women with this test result should undergo prophylactic salpingo-oophorectomy.

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b. They may be normal variants and may not represent an increased risk of ovarian and breast cancer.

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c. One third of BRCA1 test results may be classified as variant of uncertain clinical significance.

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d. One half of BRCA2 test results may be classified as variant of uncertain clinical significance.

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Which of the following statements regarding ovarian cancer screening is true?

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a. Women at average risk should undergo OvaSure testing annually.

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b. Women at average risk should undergo annual cancer antigen 125 (CA125) and transvaginal sonography screening.

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c. Currently, there is no approved screening test for women at average risk in the United States.

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d....

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