TY  - CHAP
M1  - Book, Section
TI  - Dandy–Walker Malformation and Variants
A1  - Bianchi, Diana W.
A1  - Crombleholme, Timothy M.
A1  - D'Alton, Mary E.
A1  - Malone, Fergal D.
Y1  - 2015
N1  - 
T2  - Fetology: Diagnosis and Management of the Fetal Patient, 2e
AB  - Key  PointsDandy–Walker  malformation  refers  to  the  combination  of  hypoplasia  of  the  cerebellar  vermis,  cystic  dilation  of  the  fourth  ventricle  communicating  with  the  cisterna  magna,  and  increase  in  size  of  the  posterior  fossa.Related  conditions  include  Dandy–Walker  variant  (varying  hypoplasia  of  the  inferior  vermis  without  enlargement  of  fourth  ventricle  or  cisterna  magna),  mega  cisterna  magna  (enlarged  cisterna  magna  in  the  setting  of  normal  vermis),  and  Blake’s  pouch  cyst  (extension  of  the  fourth  ventricle  into  the  cisterna  magna,  represented  by  septae  within  the  cisterna  magna).Some  authors  feel  that  there  is  no  role  in  differentiating  Dandy–Walker  malformation  and  variant,  as  both  can  be  associated  with  CNS  and  non-CNS  malformations,  aneuploidy,  and  adverse  neurological  outcome.False-positive  diagnoses  of  Dandy–Walker  malformation  are  possible,  especially  if  noted  before  18  weeks,  or  if  the  abnormality  is  confined  to  the  cerebellar  vermis  alone.Following  diagnosis,  a  detailed  search  for  other  CNS  and  non-CNS  malformations  is  required,  including  prenatal  MRI,  and  karyotype  analysis.Other  than  multidisciplinary  counseling,  no  other  alterations  to  standard  obstetric  care  are  indicated.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - obgyn.mhmedical.com/content.aspx?aid=1106396308
ER  -