TY - CHAP M1 - Book, Section TI - Atrial Septal Defects A1 - Bianchi, Diana W. A1 - Crombleholme, Timothy M. A1 - D'Alton, Mary E. A1 - Malone, Fergal D. Y1 - 2015 N1 - T2 - Fetology: Diagnosis and Management of the Fetal Patient, 2e AB - Key PointsAtrial septal defects are relatively common congential cardiac malformations, but are difficult to diagnose prenatally due to problems differentiating the normal patent foramen ovale from an anatomic defect of the septum.Many cases close spontaneously within 2 years of life, while persistence of a large defect, especially with evidence of right ventricular overload, is an indication for elective closure.Open surgical approaches to closure have been replaced in most cases with minimally invasive transcatheter occlusion techniques.While the medium-term outcome of such transcatheter occlusion techniques appears favorable, it will likely be some time before sufficient data are available to confirm long-term safety and efficacy. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - obgyn.mhmedical.com/content.aspx?aid=1106397832 ER -