TY - CHAP M1 - Book, Section TI - Tetralogy of Fallot A1 - Bianchi, Diana W. A1 - Crombleholme, Timothy M. A1 - D'Alton, Mary E. A1 - Malone, Fergal D. Y1 - 2015 N1 - T2 - Fetology: Diagnosis and Management of the Fetal Patient, 2e AB - Key PointsTetralogy of Fallot is a complex congenital cardiac malformation consisting of varying degrees of right ventricular outflow tract obstruction, ventricular septal defect, overriding aorta and right ventricular hypertrophy (although the latter is generally not present in fetal life).Prenatal diagnosis generally requires careful evaluation of cardiac outflow tracts, including discontinuity between ventricular septum and aortic outflow, as well as a relatively small pulmonary outflow.Testing for fetal karyotype and 22q11 deletion is recommended.Infants should be delivered in a controlled setting with ability to provide prostaglandin infusion and prompt pediatric cardiology availability.While initial palliation with a systemic-to-pulmonary arterial shunt may be required, many centers today perform definitive complete surgical correction within the first 6 months of life. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - obgyn.mhmedical.com/content.aspx?aid=1106398194 ER -