TY  - CHAP
M1  - Book, Section
TI  - Radial Aplasia
A1  - Bianchi, Diana W.
A1  - Crombleholme, Timothy M.
A1  - D'Alton, Mary E.
A1  - Malone, Fergal D.
PY  - 2015
T2  - Fetology: Diagnosis and Management of the Fetal Patient, 2e
AB  - Key  PointsDefect  occurs  on  the  radial  (formerly  preaxial)  side  of  the  forearm.  Findings  may  include  absence  or  hypoplasia  of  the  radius,  absence  or  hypoplasia  of  the  scaphoid  and  trapezium  bones  of  the  wrist,  or  abnormalities  of  the  thumb  and  the  first  metacarpal.Radial  deformities  may  be  associated  with  hematologic  abnormalities.Incidence  is  1  in  30,000.  Occurs  bilaterally  in  50%  of  cases.May  be  diagnosed  as  early  as  14-15  weeks.  Sonographically,  a  single  forearm  bone  is  seen  with  radial  deviation  of  the  hand.Differential  diagnosis  includes  chromosome  abnormalities,  single-gene  (dominant  or  recessive)  disorders,  teratogen  exposure,  and  multiple  congenital  anomaly  syndromes.Should  exclude  trisomy  18  by  performing  a  karyotype.Delivery  is  recommended  at  a  tertiary  center  to  permit  consultation  with  genetics,  radiology,  and  orthopedics.Recurrence  risk  depends  on  underlying  condition.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/20
UR  - obgyn.mhmedical.com/content.aspx?aid=1106400695
ER  -