RT Book, Section A1 Charlamb, Jayne R. A2 Silverman, Robert K. SR Print(0) ID 1139757275 T1 Obesity and Breast Development and Function T2 Obesity Medicine: Management of Obesity in Women's Health Care YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9780071843515 LK obgyn.mhmedical.com/content.aspx?aid=1139757275 RD 2024/04/19 AB During preadolescent childhood, the growth of the mammary gland is isometric, keeping pace with the general growth of the child’s body.1 At thelarche, the onset of secondary breast development occurring at puberty, the female mammary gland undergoes significant further development of its previously primitive ductal and lobular structures. It is the deposition of adipose tissue within the mammary gland, however, that accounts for the majority of the increase in breast size associated with puberty.2 Body mass index (BMI) has been found to relate to both the timing of thelarche and the composition of the adult female breast.