RT Book, Section A1 Bianchi, Diana W. A1 Crombleholme, Timothy M. A1 D'Alton, Mary E. A1 Malone, Fergal D. SR Print(0) ID 1106397832 T1 Atrial Septal Defects T2 Fetology: Diagnosis and Management of the Fetal Patient, 2e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 978-0-07-144201-5 LK obgyn.mhmedical.com/content.aspx?aid=1106397832 RD 2024/04/23 AB Key PointsAtrial septal defects are relatively common congential cardiac malformations, but are difficult to diagnose prenatally due to problems differentiating the normal patent foramen ovale from an anatomic defect of the septum.Many cases close spontaneously within 2 years of life, while persistence of a large defect, especially with evidence of right ventricular overload, is an indication for elective closure.Open surgical approaches to closure have been replaced in most cases with minimally invasive transcatheter occlusion techniques.While the medium-term outcome of such transcatheter occlusion techniques appears favorable, it will likely be some time before sufficient data are available to confirm long-term safety and efficacy.