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Fetal Disorders

What is the most common cause of fetal anemia?

a. Alpha thalassemia

b. Fetomaternal hemorrhage

c. Parvovirus B19 infection

d. Red cell alloimmunization

What is the approximate prevalence of red cell alloimmunization in pregnancy?

a. 0.1%

b. 1%

c. 5%

d. 8%

Most cases of severe fetal anemia secondary to alloimmunization are due to all EXCEPT which of the following antibodies?

a. Anti-c

b. Anti-d

c. Anti-D

d. Anti-Kell

What is the critical titer for anti-D antibody alloimmunization?

a. 1:4

b. 1:8

c. 1:16

d. 1:32

What is the minimum amount of fetal erythrocytes needed in the maternal circulation to provoke sensitization to D antigen?

a. 0.01 mL

b. 0.1 mL

c. 1 mL

d. 5 mL

A mother whose blood type is A negative labors and delivers a B-positive child at term. She does not receive anti-D immune globulin postpartum. What are the chances that the patient will become alloimmunized?

a. 2%

b. 8%

c. 20%

d. 33%

All EXCEPT which of the following antibodies are harmless in pregnancy?

a. Anti-I

b. Anti-Lua

c. Anti-Fyb

d. Anti-Lewis

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