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Thromboembolic Disorders

What is the approximate incidence of thromboembolic events per pregnancy?

a. 1/10

b. 1/100

c. 1/1000

d. 1/10,000

Which of the following statements is correct regarding the timing of pregnancy-related deep-vein thrombosis (DVT) and pulmonary embolism (PE)?

a. DVT and PE are more common antepartum.

b. DVT and PE are more common postpartum.

c. DVT is more common antepartum, and PE is more common postpartum.

d. PE is more common antepartum, and DVT is more common postpartum.

All EXCEPT which of the following physiologic alterations predispose to venous thrombosis in pregnancy?

a. Lower extremity venous stasis

b. Decreased plasminogen activity

c. Endothelial cell injury at delivery

d. Increased synthesis of clotting factors

Which of the following risk factors for developing thromboembolism in pregnancy is most important?

a. Cesarean delivery

b. Multifetal gestation

c. Postpartum hemorrhage

d. Personal history of thrombosis

Approximately what percentage of thromboembolic events that occur during pregnancy can be attributed to an inherited or acquired thrombophilia?

a. 1%

b. 15%

c. 50%

d. 75%

The mutations that cause antithrombin deficiency are almost always inherited in what fashion?

a. X-linked dominant

b. X-linked recessive

c. Autosomal dominant

d. Autosomal recessive

Understanding pregnancy physiology is essential to diagnose protein S deficiency. Concentrations of which of the following decline substantially during normal pregnancy?

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