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Pediatric Gynecology

Which of the following statements is FALSE regarding the development of the hypothalamic–pituitary-ovarian axis in the female fetus and neonate?

a. By 5 months’ gestation, 6 to 7 million oocytes have been created from accelerated germ cell division.

b. The gonadotropin-releasing hormone (GnRH) “pulse generator” remains functionally dormant until several months after birth.

c. At birth, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) concentrations rise and remain high during the first 3 months of life.

d. Neonatal breast budding, minor uterine bleeding, and transient ovarian cysts may occur as a normal response to initially high gonadotropin levels.

Which of the following statements is true regarding pelvic anatomy in the female infant and child?

a. The ovaries have obtained their normal adult size by birth.

b. At birth, the uterus and cervix are approximately equal in size.

c. Presence of an endometrial stripe or fluid within the endometrial cavity of the newborn uterus is a normal finding with sonography.

d. All the above are true statements.

Which of the following generally occurs first among the major developmental events of female puberty?

a. Menarche

b. Pubarche

c. Thelarche

d. Growth spurt

An alarmed parent brings her 8-year-old daughter in for evaluation of breast budding. The child shows no other signs of puberty. Precocious puberty is defined as initial pubertal changes occurring prior to what threshold age?

a. 6 years

b. 7 years

c. 8 years

d. 9 years

Delayed puberty is characterized by a lack of initial pubertal changes, usually thelarche, by what threshold age?

a. 13 years

b. 14 years

c. 15 years

d. 16 years

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