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Reproductive Endocrinology

Which of the following most accurately describes autocrine hormone communication?

a. A cell secretes a hormone that acts on a neighboring cell.

b. A cell secretes a hormone that influences its own function.

c. The hormone is secreted and acts upon a distant target tissue.

d. The hormone produced acts within the cell before it is secreted.

The figure below portrays which type of hormone action?

Reproduced with permission from Hoffman BL, Schorge JO, Bradshaw KD, et al: Williams Gynecology, 3rd ed. New York, McGraw-Hill, 2016. Figure 15-1B.

a. Autocrine

b. Endocrine

c. Paracrine

d. Intracrine

Which of the following statements is true regarding the gonadotropin luteinizing hormone (LH)?

a. It is secreted by the posterior pituitary gland.

b. Its functional specificity is derived from the α-subunit.

c. It shares a common glycoprotein β-subunit with follicle-stimulating hormone (FSH).

d. Its β-subunit demonstrates approximately 80 percent homology with that of human chorionic gonadotropin (hCG).

A 48-year-old woman presents to the Emergency Department with severe upper abdominal pain and a positive pregnancy test. She has had a prior tubal ligation. A computed tomography scan performed to evaluate her pain is significant for multiple heterogeneous hepatic lesions (shown below). Her serum β-human chorionic gonadotropin (β-hCG) test result is 115 mIU/mL. Transvaginal sonography results are also shown below. Chest radiographs are normal. What is the most likely source of her hCG?

a. Liver tumors

b. Exogenous hCG injection

c. Partial molar pregnancy

d. Complete molar pregnancy

Which of the following statements regarding steroidogenesis is FALSE?


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