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In those without menses, which of the following clinical scenarios meets the definition of amenorrhea?

a. A 12-year-old woman with Tanner stage I breast development

b. A 16-year-old woman with Tanner stage II breast development

c. A14-year-old woman with Tanner stage III breast development

d. An 18-year-old woman with Tanner stage V breast development and cessation of menses for the last two cycles

A rapid rise in which hormone is necessary to trigger ovulation?

a. Estrogen

b. Progesterone

c. Follicle-stimulating hormone (FSH)

d. Human chorionic gonadotropin (hCG)

Which of the following hormones “rescues” the corpus luteum from luteolysis?

a. Luteinizing hormone

b. Human placental lactogen

c. Follicle-stimulating hormone (FSH)

d. Human chorionic gonadotropin (hCG)

A 16-year-old woman presents for evaluation of pelvic pain. She has advanced breast and sexual hair development. Her examination is significant for the finding below. A transvaginal ultrasound shows normal female pelvic anatomy. What is this patient’s expected karyotype?

Used with permission from Dr. Ellen Wilson.

a. 45,X

b. 46,XX

c. 46,XY

d. 45,X/46,XX

Which of the following is NOT derived from the müllerian ducts?

a. Cervix

b. Lower vagina

c. Upper vagina

d. Fallopian tube

An 18-year-old nulligravida presents with primary amenorrhea. Her examination is notable for Tanner stage IV breasts and the absence of pubic and axillary hair. Also, a blind ending vagina is identified. What is the likely diagnosis in this patient?

a. Müllerian agenesis


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