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Uterine Sarcoma

Which of the following sarcomas are mixed tumors demonstrating both malignant epithelial and malignant stromal components?

a. Adenosarcomas

b. Carcinosarcomas

c. Leiomyosarcomas

d. Endometrial stromal sarcomas

Which of the following was previously termed malignant mixed müllerian tumor (MMMT)?

a. Adenosarcoma

b. Carcinosarcoma

c. Leiomyosarcoma

d. Endometrial stromal tumors

Which of the following is generally true of uterine sarcomas and carcinosarcomas compared with other types of gynecologic malignancy?

a. They are slow growing.

b. Overall prognosis is favorable.

c. Lymphatic or hematogenous spread occurs early.

d. All of the above

Sarcomas account for approximately what percentage of uterine cancer?

a. 0.5 to 1 percent

b. 3 to 8 percent

c. 15 to 20 percent

d. 28 to 32 percent

Which of the following tumor types has been reclassified as a metaplastic form of endometrial carcinoma?

a. Adenosarcoma

b. Carcinosarcoma

c. Leiomyosarcoma

d. Endometrial stromal tumors

Due to the rarity of uterine sarcomas and carcinosarcomas, it is difficult to ascertain risk factors for them. Which of the following is NOT a suspected risk factor for these tumors?

a. African-American race

b. Oral contraceptive use

c. Prior pelvic radiation

d. Excess estrogen exposure or tamoxifen use

Which of the following is true regarding the pathogenesis of leiomyosarcomas?

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