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APPENDIX I: Serum and Blood Constituents

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HEMATOLOGY
Nonpregnant Adulta 1st Trimester 2nd Trimester 3rd Trimester References
Erythropoietinb (U/L) 4–27 12–25 8–67 14–222 7, 10, 47
Ferritinb (ng/mL) 10–150d 6–130 2–230 0–116 7, 10, 39, 42, 45, 47, 62, 70
Folate, red blood cell (ng/mL) 150–450 137–589 94–828 109–663 45, 46, 72
Folate, serum (ng/mL) 5.4–18.0 2.6–15.0 0.8–24.0 1.4–20.7 7, 43, 45, 46, 53, 58, 72
Haptoglobin (mg/mL) 25–250 130 ± 43 115 ± 50 135 ± 65 26A
Hemoglobinb (g/dL) 12–15.8d 11.6–13.9 9.7–14.8 9.5–15.0 10, 45, 47, 58, 62
Hematocritb (%) 35.4–44.4 31.0–41.0 30.0–39.0 28.0–40.0 6, 7, 10, 42, 45 58, 66
Iron, total binding capacity (TIBC)b (μg/dL) 251–406 278–403 Not reported 359–609 62
Iron, serumb (μg/dL) 41–141 72–143 44–178 30–193 10, 62
Mean corpuscular hemoglobin (MCH) (pg/cell) 27–32 30–32 30–33 29–32 42
Mean corpuscular volume (MCV) (×m3) 79–93 81–96 82–97 81–99 6, 42, 45, 58
Platelet (×109/L) 165–415 174–391 155–409 146–429 4, 6, 16, 42, 45
Mean platelet volume (MPV) (μm3) 6.4–11.0 7.7–10.3 7.8–10.2 8.2–10.4 42
Red blood cell count (RBC) (×106/mm3) 4.00–5.20d 3.42–4.55 2.81–4.49 2.71–4.43 6, 42, 45, 58
Red cell distribution width (RDW) (%) <14.5 12.5–14.1 13.4–13.6 12.7–15.3 42
White blood cell count (WBC) (×103/mm3) 3.5–9.1 5.7–13.6 5.6–14.8 5.9–16.9 6, 9, 42, 45, 58
Neutrophils (×103/mm3) 1.4–4.6 3.6–10.1 3.8–12.3 3.9–13.1 4, 6, 9, 42
Lymphocytes (×103/mm3) 0.7–4.6 1.1–3.6 0.9–3.9 1.0–3.6 4, 6, 9, 42
Monocytes (×103/mm3) 0.1–0.7 0.1–1.1 0.1–1.1 0.1–1.4 6, 9, 42
Eosinophils (×103/mm3) 0–0.6 0–0.6 0–0.6 0–0.6 6, 9
Basophils (×103/mm3) 0–0.2 0–0.1 0–0.1 0–0.1 6, 9
Transferrin (mg/dL) 200–400c 254–344 220–441 288–530 39, 42
Transferrin, saturation without iron (%) 22–46b Not reported 10–44 5–37 47
Transferrin, saturation with iron (%) 22–46b Not reported 18–92 9–98 47
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COAGULATION
Nonpregnant Adulta 1st Trimester 2nd Trimester 3rd Trimester References
Antithrombin III, functional (%) 70–130 89–114 78–126 82–116 15, 16, 39A
D-Dimer (μg/mL) 0.22–0.74 0.05–0.95 0.32–1.29 0.13–1.7 16, 25, 25C, 35, 39A, 41A, 51
Factor V (%) 50–150 75–95 72–96 60–88 40
Factor VII (%) 50–150 100–146 95–153 149–2110 16
Factor VIII (%) 50–150 90–210 97–312 143–353 16, 40
Factor IX (%) 50–150 103–172 154–217 164–235 16
Factor XI (%) 50–150 80–127 82–144 65–123 16
Factor XII (%) 50–150 78–124 90–151 129–194 16
Fibrinogen (mg/dL) 233–496 244–510 291–538 301–696 16, 25, 25C, 39A, 41A, 42, 51
Fibronectin (mg/L)

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