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Teratology, Teratogens, and Fetotoxic Agents

What percentage of all newborns have a major congenital abnormality detected at birth?

a. 2–3%

b. 4%

c. 5%

d. 7%

The majority of birth defects with an identifiable etiology are caused by which of the following?

a. Multiple gestations

b. Medication exposure

c. Environmental toxins

d. Chromosome abnormality

What percentage of all birth defects are the result of medication exposure?

a. 2%

b. 6%

c. 10%

d. <1%

Approximately how many medications do women take while pregnant?

a. 0

b. 1

c. 1–3

d. 2–3

For what percentage of medications approved by the Food and Drug Administration is the pregnancy risk known?

a. 75%

b. 80%

c. <5%

d. <10%

Which of the following accurately defines a teratogen?

a. An agent that alters growth

b. An agent that interferes with normal maturation and function of an organ

c. An agent that acts during embryonic or fetal development to produce a permanent alteration of form or function

d. All of the above

All except which of the following are essential in the criteria for determining teratogenicity?

a. Careful delineation of clinical cases

b. Animal studies showing ...

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