TY - CHAP M1 - Book, Section TI - Serum and Blood Constituents A1 - Cunningham, F. Gary A1 - Leveno, Kenneth J. A1 - Bloom, Steven L. A1 - Dashe, Jodi S. A1 - Hoffman, Barbara L. A1 - Casey, Brian M. A1 - Spong, Catherine Y. PY - 2018 T2 - Williams Obstetrics, 25e AB - Table Graphic Jump LocationView Table||Download (.pdf)HEMATOLOGYNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesErythropoietinb (U/L)4–2712–258–6714–2227, 10, 47Ferritinb (ng/mL)10–150d6–1302–2300–1167, 10, 39, 42, 45, 47, 62, 70Folate, red blood cell (ng/mL)150–450137–58994–828109–66345, 46, 72Folate, serum (ng/mL)5.4–18.02.6–15.00.8–24.01.4–20.77, 43, 45, 46, 53, 58, 72Haptoglobin (mg/mL)25–250130 ± 43115 ± 50135 ± 6526AHemoglobinb (g/dL)12–15.8d11.6–13.99.7–14.89.5–15.010, 45, 47, 58, 62Hematocritb (%)35.4–44.431.0–41.030.0–39.028.0–40.06, 7, 10, 42, 4558, 66Iron, total binding capacity (TIBC)b (μg/dL)251–406278–403Not reported359–60962Iron, serumb (μg/dL)41–14172–14344–17830–19310, 62Mean corpuscular hemoglobin (MCH) (pg/cell)27–3230–3230–3329–3242Mean corpuscular volume (MCV) (×m3)79–9381–9682–9781–996, 42, 45, 58Platelet (×109/L)165–415174–391155–409146–4294, 6, 16, 42, 45Mean platelet volume (MPV) (μm3)6.4–11.07.7–10.37.8–10.28.2–10.442Red blood cell count (RBC) (×106/mm3)4.00–5.20d3.42–4.552.81–4.492.71–4.436, 42, 45, 58Red cell distribution width (RDW) (%)<14.512.5–14.113.4–13.612.7–15.342White blood cell count (WBC) (×103/mm3)3.5–9.15.7–13.65.6–14.85.9–16.96, 9, 42, 45, 58Neutrophils (×103/mm3)1.4–4.63.6–10.13.8–12.33.9–13.14, 6, 9, 42Lymphocytes (×103/mm3)0.7–4.61.1–3.60.9–3.91.0–3.64, 6, 9, 42Monocytes (×103/mm3)0.1–0.70.1–1.10.1–1.10.1–1.46, 9, 42Eosinophils (×103/mm3)0–0.60–0.60–0.60–0.66, 9Basophils (×103/mm3)0–0.20–0.10–0.10–0.16, 9Transferrin (mg/dL)200–400c254–344220–441288–53039, 42Transferrin, saturation without iron (%)22–46bNot reported10–445–3747Transferrin, saturation with iron (%)22–46bNot reported18–929–9847COAGULATIONNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesAntithrombin III, functional (%)70–13089–11478–12682–11615, 16, 39AD-Dimer (μg/mL)0.22–0.740.05–0.950.32–1.290.13–1.716, 25, 25C, 35, 39A, 41A, 51Factor V (%)50–15075–9572–9660–8840Factor VII (%)50–150100–14695–153149–211016Factor VIII (%)50–15090–21097–312143–35316, 40Factor IX (%)50–150103–172154–217164–23516Factor XI (%)50–15080–12782–14465–12316Factor XII (%)50–15078–12490–151129–19416Fibrinogen (mg/dL)233–496244–510291–538301–69616, 25, 25C, 39A, 41A, 42, 51Fibronectin (mg/L)290 ± 85377 ± 309315 ± 295334 ± 25727AHomocysteine (μmol/L)4.4–10.83.34–112.0–26.93.2–21.443, 45, 46, 53, 72International normalized ratio (INR)0.9–1.04g0.86–1.080.83–1.020.80–1.0915, 41APartial thromboplastin time, activated (aPTT) (sec)26.3–39.423.0–38.922.9–38.122.6–35.015, 16, 41A, 42Prothrombin time (PT) (sec)12.7–15.49.7–13.59.5–13.49.6–12.916, 41A, 42Protein C, functional (%)70–13078–12183–13367–13515, 24, 40Protein S, total (%)70–14039–10527–10133–10116, 24, 40Protein S, free (%)70–14034–13319–11320–6524, 40Protein S, functional activity (%)65–14057–9542–6816–4240Thrombin time (TT) (sec)17.7 ± 2.816.1 ± 1.515.4 ± 2.716.5 ± 2.427AThrombomodulin (ng/mL)2.7 ± 3.14.3 ± 1.34.2 ± 1.23.6 ± 1.327ATissue plasminogen activator (ng/mL)1.6–13h1.8–6.02.36–6.63.34–9.2015, 16, 25CTissue plasminogen activator inhibitor-1 (ng/mL)4–4316–3336–5567–9216, 25Cvon Willebrand disease von Willebrand factor antigen (%)75–12562–31890–24784–42239A, 44A, 73ADAMTS-13, von Willebrand cleaving protease (%)40–170i40–16022–13538–10539A, 44ABLOOD CHEMICAL CONSTITUTENTSNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesAlanine aminotransferase (ALT) (U/L)7–413–302–332–255, 39, 42, 70Albumin (g/dL)4.1–5.3d3.1–5.12.6–4.52.3–4.23, 5, 26, 29, 39, 42, 72Alkaline phosphatase (U/L)33–9617–8825–12638–2293, 5, 39, 42, 70Alpha-1 antitrypsin (mg/dL)100–200225–323273–391327–48742Alpha-fetoprotein (ng/mL)——∼130–400∼130–59039BAmmonia (μM)31 ± 3.2——27.3 ± 1.631AAmylase (U/L)20–9624–8316–7315–8132, 39, 42, 68Anion gap (mmol/L)7–1613–1712–1612–1642Aspartate aminotransferase (AST) (U/L)12–383–233–334–325, 39, 42, 70Bicarbonate (mmol/L)22–3020–2420–2420–2442Bilirubin, total (mg/dL)0.3–1.30.1–0.40.1–0.80.1–1.15, 39Bilirubin, unconjugated (mg/dL)0.2–0.90.1–0.50.1–0.40.1–0.55, 42Bilirubin, conjugated (mg/dL)0.1–0.40–0.10–0.10–0.15Bile acids (μmol/L)0.3–4.8j0–4.90–9.10–11.35, 14CA-125 (μg/mL)7.2–272.2–26812–25.116.8–43.83A, 30A, 67ACalcium, ionized (mg/dL)4.5–5.34.5–5.14.4–5.04.4–5.326, 42, 48, 56Calcium, total (mg/dL)8.7–10.28.8–10.68.2–9.08.2–9.73, 29, 39, 42, 48, 56, 63Ceruloplasmin (mg/dL)25–6330–4940–5343–7842, 44Chloride (mEq/L)102–109101–10597–10997–10920, 39, 42Creatinine (mg/dL)0.5–0.9d0.4–0.70.4–0.80.4–0.939, 42, 45Gamma-glutamyl transpeptidase (GGT) (U/L)9–582–234–223–265, 42, 39, 70Lactate dehydrogenase (U/L)115–22178–43380–44782–52442, 29, 39, 70Lipase (U/L)3–4321–7626–10041–11232Magnesium (mg/dL)1.5–2.31.6–2.21.5–2.21.1–2.23, 26, 29, 39, 42, 48, 63Osmolality (mOsm/kg H2O)275–295275–280276–289278–28017, 63Phosphate (mg/dL)2.5–4.33.1–4.62.5–4.62.8–4.63, 26, 33, 39, 42Potassium (mEq/L)3.5–5.03.6–5.03.3–5.03.3–5.120, 26, 29, 39, 42, 63, 66Prealbumin (mg/dL)17–3415–2720–2714–2342Protein, total (g/dL)6.7–8.66.2–7.65.7–6.95.6–6.726, 29, 42Sodium (mEq/L)136–146133–148129–148130–14817, 26, 29, 39, 42, 63, 66Urea nitrogen (mg/dL)7–207–123–133–1120, 39, 42Uric acid (mg/dL)2.5–5.6d2.0–4.22.4–4.93.1–6.317, 39, 42METABOLIC AND ENDOCRINE TESTSNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesAldosterone (ng/dL)2–96–1049–10415–10121, 34, 69Angiotensin-converting enzyme (ACE) (U/L)9–671–381–361–3920, 54Cortisol (μg/dL)0–257–1910–4212–5042, 69Hemoglobin A1C (%)4–64–64–64–748, 49, 59Parathyroid hormone (pg/mL)8–5110–1518–259–263Parathyroid hormone-related protein (pmol/L)<1.3e0.7–0.91.8–2.22.5–2.83Renin, plasma activity (ng/mL/hr)0.3–9.0eNot reported7.5–54.05.9–58.820, 34Thyroid stimulating hormone (TSH) (μIU/mL)0.34–4.250.60–3.400.37–3.600.38–4.0439, 42, 57Thyroxine-binding globulin (mg/dL)1.3–3.01.8–3.22.8–4.02.6–4.242Thyroxine, free (fT4) (ng/dL)0.8–1.70.8–1.20.6–1.00.5–0.842, 57Thyroxine, total (T4) (μg/dL)5.4–11.76.5–10.17.5–10.36.3–9.729, 42Triiodothyronine, free (fT3) (pg/mL)2.4–4.24.1–4.44.0–4.2Not reported57Triiodothyronine, total (T3) (ng/dL)77–13597–149117–169123–16242VITAMINS AND MINERALSNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesCopper (μg/dL)70–140112–199165–221130–2402, 30, 42Selenium (μg/L)63–160116–14675–14571–1332, 42Vitamin A (retinol) (μg/dL)20–10032–4735–4429–4242Vitamin B12 (pg/mL)279–966118–438130–65699–52645, 72Vitamin C (ascorbic acid) (mg/dL)0.4–1.0Not reportedNot reported0.9–1.364Vitamin D, 1,25-dihydroxy (pg/mL)25–4520–6572–16060–1193, 48Vitamin D, 24,25-dihydroxy (ng/mL)0.5–5.0e1.2–1.81.1–1.50.7–0.960Vitamin D, 25-hydroxy (ng/mL)14–8018–2710–2210–183, 60Vitamin E (α-tocopherol) (μg/mL)5–187–1310–1613–2342Zinc (μg/dL)75–12057–8851–8050–772, 42, 58AUTOIMMUNE AND INFLAMMATORY MEDIATORSNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesC3 complement (mg/dL)83–17762–9873–10377–11142C4 complement (mg/dL)16–4718–3618–3422–3242C-reactive protein (CRP) ... SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/23 UR - obgyn.mhmedical.com/content.aspx?aid=1160782562 ER -