TY - CHAP M1 - Book, Section TI - Preterm Birth A1 - Cunningham, F. Gary A1 - Leveno, Kenneth J. A1 - Bloom, Steven L. A1 - Dashe, Jodi S. A1 - Hoffman, Barbara L. A1 - Casey, Brian M. A1 - Spong, Catherine Y. PY - 2018 T2 - Williams Obstetrics, 25e AB - It is generally admitted that there exists in the medulla a centre for uterine contractions, which can be stimulated by an excess of carbon dioxide in the blood, by anaemia and the presence of various toxic substances; and it seems highly probable that the frequency of premature labour in cases of renal insufficiency and eclampsia may be due to the action of metabolic poisons upon the centre.—J. Whitridge Williams (1903) SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - obgyn.mhmedical.com/content.aspx?aid=1197209303 ER -