TY - CHAP M1 - Book, Section TI - Intrauterine Infections Affecting the Brain A1 - Malinger, Gustavo A1 - Malinger, Andrés A1 - Wolman, Igal A1 - Krajden-Haratz, Karina A2 - Malinger, Gustavo A2 - Monteagudo, Ana A2 - Pilu, Gianluigi A2 - Paladini, Dario A2 - Timor-Tritsch, Ilan E. PY - 2023 T2 - Timor's Ultrasonography of the Prenatal Brain, 4e AB - KEY POINTSDepending on geographic factors, cytomegalovirus (CMV) and toxoplasmosis are the more frequent intrauterine infections.The pattern of brain involvement in CMV–IUI may range from minimal (small periventricular cysts, intrathalamic vasculopathy) to severe damage (brain atrophy, malformations of cortical development, hemorrhages).Regardless the etiology, the prognosis is usually poor in the presence of intracranial findings.CMV infected fetuses without brain findings are generally asymptomatic at birth but may develop sensorineural deafness.In patients at risk, search systematically for signs of infection. Check the placenta, liver, intestines, and brain (ventriculomegaly, abnormal periventricular white matter, cysts, etc).In low-risk patients, these signs may be the only clue for prenatal diagnosis. SN - PB - McGraw Hill Education CY - New York, NY Y2 - 2024/10/03 UR - obgyn.mhmedical.com/content.aspx?aid=1194720315 ER -