TY - CHAP M1 - Book, Section TI - Chapter 17. Multiple Gestation A1 - Bush, Melissa C. A1 - Pernoll, Martin L. A2 - DeCherney, Alan H. A2 - Nathan, Lauren A2 - Laufer, Neri A2 - Roman, Ashley S. PY - 2013 T2 - CURRENT Diagnosis & Treatment: Obstetrics & Gynecology, 11e AB - The incidence of multiple gestations has risen significantly over several decades, primarily due to increased use of fertility drugs for ovulation induction, superovulation, and assisted reproductive technologies (ART), such as in vitro fertilization (IVF).Compared with singleton pregnancies, twin pregnancies are more likely to be complicated by hypertensive disorders, gestational diabetes mellitus, anemia, preterm birth, ante- and postpartum hemorrhage, and maternal death.The perinatal mortality rate of twins is 3–4 times higher—and for triplets much higher still—than in singleton pregnancies as a result of chromosomal abnormalities, prematurity, structural anomalies, hypoxia, and trauma.This is particularly true of monozygotic twins, which are also uniquely susceptible to twin–twin transfusion syndrome. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - obgyn.mhmedical.com/content.aspx?aid=56967022 ER -