TY - CHAP M1 - Book, Section TI - Truncus Arteriosus A1 - Bianchi, Diana W. A1 - Crombleholme, Timothy M. A1 - D'Alton, Mary E. A1 - Malone, Fergal D. PY - 2015 T2 - Fetology: Diagnosis and Management of the Fetal Patient, 2e AB - Key PointsTruncus arteriosus is a rare form of congenital cardiac disease in which a single cardiac outflow tract gives rise to the pulmonary, coronary, and systemic circulations.Prenatal diagnosis relies upon failure to visualize three separate vessels in a transverse view through the upper mediastinum, and failure to visualize the normal branch pulmonary arteries and their origin from the right ventricle.Up to 40% of cases are associated with a 22q11 deletion and the DiGeorge syndrome, thereby making amniocentesis a crucial part of the prenatal diagnostic evaluation.While timing and mode of delivery do not need to be altered following the diagnosis, planned delivery in a tertiary care setting with appropriate pediatric cardiology backup is critical, as congestive cardiac failure can occur in the neonatal period.Early definitive surgical repair is recommended, typically by means of a homograft from the right ventricle to the pulmonary artery, with closure of a VSD.Long-term survival rates of 80% can be expected. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - obgyn.mhmedical.com/content.aspx?aid=1106398280 ER -