TY - CHAP M1 - Book, Section TI - Imperforate Anus A1 - Bianchi, Diana W. A1 - Crombleholme, Timothy M. A1 - D'Alton, Mary E. A1 - Malone, Fergal D. PY - 2015 T2 - Fetology: Diagnosis and Management of the Fetal Patient, 2e AB - Key PointsIncidence is 1 in 5,000 livebirths. Has been linked to maternal diabetes, thalidomide, ethanol, and assisted reproductive technology.Imperforate anus is difficult to diagnose by prenatal sonographic studies.Sonographic findings that may be due to imperforate anus include transient bowel dilation in first trimester, intraluminal calcifications in the colon, and persistent distal bowel dilation later in gestation.Fetal MRI may be an important adjunct to ultrasound examination if anorectal malformation is suspected.50% of anorectal malformations have associated anomalies of the spine, limbs, genitourinary system, trachea, esophagus and the heart. Echocardiogram is indicated.Associated with many syndromes and chromosome abnormalities. Amniocentesis is indicated for fetal karyotype.Delivery should occur in a tertiary care center with pediatric surgical, radiologic, and genetic expertise available.Bowel continence is usually achieved in 90% of patients. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - obgyn.mhmedical.com/content.aspx?aid=1106399297 ER -