TY - CHAP M1 - Book, Section TI - Intrauterine Death in One Twin A1 - Bianchi, Diana W. A1 - Crombleholme, Timothy M. A1 - D'Alton, Mary E. A1 - Malone, Fergal D. PY - 2015 T2 - Fetology: Diagnosis and Management of the Fetal Patient, 2e AB - Key PointsIntrauterine fetal death (IUFD) of one twin in the first trimester is common and is known as a “vanishing twin.”Although a “vanishing twin” may be associated with vaginal spotting, it is not associated with adverse perinatal outcomes for the surviving twin.Single IUFD in the second and third trimester is less common and is more likely to be associated with complications for the surviving co-twin.When single IUFD occurs in a monochorionic pregnancy, it is associated with a worse prognosis, including up to 20% incidence of significant neurologic morbidity for the surviving co-twin, such as multicystic encephalomalacia.Sonographic assessment of a single IUFD in a twin pregnancy should include determination of chorionicity, the accuracy of which may be limited in the second and third trimesters.If a certain diagnosis of chorionicity is needed for pregnancy management, DNA studies on amniocytes may be needed.Management of a case of single IUFD depends on gestational age and chorionicity.Preterm labor and delivery is often associated with single IUFD. Otherwise, expectant management is suggested if the gestational age is less than or equal to 37 completed weeks and there are no indications for delivery.Surviving co-twins in a monochorionic pregnancy should be evaluated postnatally for neurologic sequelae. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - obgyn.mhmedical.com/content.aspx?aid=1106401245 ER -