TY - CHAP M1 - Book, Section TI - Disorders of Sexual Differentiation A1 - Hogge, W. Allen A1 - Rajkovic, Aleksandar PY - 2015 T2 - Practical Genetics for the Ob-Gyn AB - Case 1: Ms. Omotoya Bamidele is a 28-year-old medical student of Yoruban origin who presented to her OB/GYN with difficulty in vaginal intercourse. She describes painful intercourse, and says that her vagina is too small. Her family is originally from Nigeria and her parents had nine children, all girls, three of which are in their 30s and unable to have children. Her sisters are unwilling to discuss their infertility, although she describes them as phenotypic females. Ms. Bamidele does not remember having a menstrual period, but did not seek medical care as she felt fine. At the age of 19, her gynecologist could not identify a cervix, and transabdominal ultrasound did not reveal the presence of uterus. She was told that she can never have children, but her parents did not want to pursue further evaluation, believing that everything would be fine. Her current physical examination was significant for scant axillary hair, normal breast development, normal labia and clitoris, with a short vaginal length of 5 cm and absence of cervix. Bimanual exam could not palpate a uterus. Although her major complaint was difficult intercourse, she wondered why she could not have children. What investigation would you pursue in order to make the diagnosis? SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - obgyn.mhmedical.com/content.aspx?aid=1115993237 ER -