TY - CHAP M1 - Book, Section TI - Premalignant & Malignant Disorders of the Vulva & Vagina A1 - Karam, Amer A2 - DeCherney, Alan H. A2 - Nathan, Lauren A2 - Laufer, Neri A2 - Roman, Ashley S. Y1 - 2019 N1 - T2 - CURRENT Diagnosis & Treatment: Obstetrics & Gynecology, 12e AB - ESSENTIALS OF DIAGNOSISPossibly 1–2% of young women with cervical dysplasia have multifocal disease that tends to involve the upper third of the vagina and the vulva, perineum, and perianal areas—these surfaces arising from a common cloacogenic origin.A spectrum of disease may be found ranging from mild dysplasia to carcinoma in situ. Involvement may not be appreciated without careful inspection with and without the green colposcopy filter. Clinically, the appearance of vulvar intraepithelial neoplasia can be quite variable.Lesions are typically white and hyperkeratotic but may also appear gray, pink, or brown.Colposcopy and biopsy of any suspicious lesion should be performed and are considered the gold standard for diagnosis.An abnormal vascular pattern is most frequently associated with a severe degree of dysplasia, carcinoma in situ, or early invasive disease. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - obgyn.mhmedical.com/content.aspx?aid=1159960940 ER -