TY - CHAP M1 - Book, Section TI - Connective Tissue Disorders A1 - Cunningham, F. Gary A1 - Leveno, Kenneth J. A1 - Dashe, Jodi S. A1 - Hoffman, Barbara L. A1 - Spong, Catherine Y. A1 - Casey, Brian M. Y1 - 2022 N1 - T2 - Williams Obstetrics, 26e AB - Connective tissue disorders, also termed collagen vascular disorders, have two basic underlying causes. First are the immune-complex diseases, in which deposition of immune complexes causes connective tissue damage. Because these manifest by sterile inflammation—predominantly of the skin, joints, blood vessels, and kidneys—they are referred to as rheumatic diseases. Many of these immune-complex diseases are more prevalent in women, and systemic lupus erythematosus (SLE) and rheumatoid arthritis are examples. Second are the inherited disorders that involve bone, skin, cartilage, blood vessels, and basement membranes. These include Marfan syndrome, osteogenesis imperfecta, and Ehlers-Danlos syndrome. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/10/14 UR - obgyn.mhmedical.com/content.aspx?aid=1190769664 ER -