TY - CHAP M1 - Book, Section TI - Cystic Hygroma in Early Pregnancy A1 - Bianchi, Diana W. A1 - Crombleholme, Timothy M. A1 - D'Alton, Mary E. A1 - Malone, Fergal D. Y1 - 2015 N1 - T2 - Fetology: Diagnosis and Management of the Fetal Patient, 2e AB - Key PointsSeptated cystic hygroma in the first trimester is defined by extensive nuchal thickening extending along the entire length of the fetal back and in which septations are clearly visible.This finding is seen frequently in the first trimester, affecting more than one in 300 pregnancies.Given the 50% risk of fetal aneuploidy, definitive diagnostic testing with CVS should be offered immediately.Amongst the 50% of cases without aneuploidy, there is a one in two risk of major structural malformation, typically cardiac or skeletal abnormalities.If complete prenatal evaluation reveals no evidence of additional abnormality, a residual risk for abnormal pediatric outcome of 5% should be quoted. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/12/11 UR - obgyn.mhmedical.com/content.aspx?aid=1106397259 ER -