TY - CHAP M1 - Book, Section TI - Syndactyly A1 - Bianchi, Diana W. A1 - Crombleholme, Timothy M. A1 - D'Alton, Mary E. A1 - Malone, Fergal D. Y1 - 2015 N1 - T2 - Fetology: Diagnosis and Management of the Fetal Patient, 2e AB - Key PointsSyndactyly refers to apparent fusion of digits, either osseous or cutaneous.Prenatal ultrasound examination reveals an inability to distinguish separate digits of fingers or toes or to demonstrate independent movement of fingers.May be isolated or syndromic.Many syndromes are associated with craniosynostosis.Fetuses with syndactyly should undergo detailed fetal sonographic examination to look for associated anomalies.Review results ofestriol levels in maternal serum screen, as low levels are present in triploidy and Smith–Lemli–Opitz syndrome.Consider karyotype to rule out triploidy. Obtain complete family history. Review results of estriol levels in maternal serum screen.A complete physical examination of infant at birth is essential. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - obgyn.mhmedical.com/content.aspx?aid=1106400649 ER -