TY - CHAP M1 - Book, Section TI - Serum and Blood Constituents A1 - Cunningham, F. Gary A1 - Leveno, Kenneth J. A1 - Dashe, Jodi S. A1 - Hoffman, Barbara L. A1 - Spong, Catherine Y. A1 - Casey, Brian M. PY - 2022 T2 - Williams Obstetrics, 26e AB - Table Graphic Jump LocationView Table||Download (.pdf)HEMATOLOGYNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesErythropoietinb (U/L)4–2712–258–6714–2228, 11, 58Ferritinb (ng/mL)10–150d6–1302–2300–1168, 11, 46, 52, 56,58, 73, 82Folate, red blood cell (ng/mL)150–450137–58994–828109–66356, 57, 84Folate, serum (ng/mL)5.4–18.02.6–15.00.8–24.01.4–20.78, 53, 56, 57,64, 69, 84Haptoglobin (mg/mL)25–250130 ± 43115 ± 50135 ± 6531Hemoglobinb (g/dL)12–15.8d11.6–13.99.7–14.89.5–15.011, 56, 58, 69, 73Hematocritb (%)35.4–44.431.0–41.030.0–39.028.0–40.07, 8, 11, 52, 5669, 77Iron, total binding capacity (TIBC)b (μg/dL)251–406278–403Not reported359–60973Iron, serumb (μg/dL)41–14172–14344–17830–19311, 73Mean corpuscular hemoglobin (MCH) (pg/cell)27–3230–3230–3329–3252Mean corpuscular volume (MCV) (×m3)79–9381–9682–9781–997, 52, 56, 69Platelet (×109/L)165–415174–391155–409146–4295, 7, 18, 52, 56Mean platelet volume (MPV) (μm3)6.4–11.07.7–10.37.8–10.28.2–10.452Red blood cell count (RBC) (×106/mm3)4.00–5.20d3.42–4.552.81–4.492.71–4.437, 52, 56, 69Red cell distribution width (RDW) (%)<14.512.5–14.113.4–13.612.7–15.352White blood cell count (WBC) (×103/mm3)3.5–9.15.7–13.65.6–14.85.9–16.97, 10, 52, 56, 69Neutrophils (×103/mm3)1.4–4.63.6–10.13.8–12.33.9–13.15, 7, 10, 52Lymphocytes (×103/mm3)0.7–4.61.1–3.60.9–3.91.0–3.65, 7, 10, 52Monocytes (×103/mm3)0.1–0.70.1–1.10.1–1.10.1–1.47, 10, 52Eosinophils (×103/mm3)0–0.60–0.60–0.60–0.67, 10Basophils (×103/mm3)0–0.20–0.10–0.10–0.17, 10Transferrin (mg/dL)200–400c254–344220–441288–53046, 52Transferrin, saturation without iron (%)22–46bNot reported10–445–3758Transferrin, saturation with iron (%)22–46bNot reported18–929–9858COAGULATIONNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesAntithrombin III, functional (%)70–13089–11478–12682–11617, 18, 47d-Dimer (μg/mL)0.22–0.740.05–0.950.32–1.290.13–1.718, 28, 29, 43, 47, 51, 62Factor V (%)50–15075–9572–9660–8849Factor VII (%)50–150100–14695–153149–211018Factor VIII (%)50–15090–21097–312143–35318, 49Factor IX (%)50–150103–172154–217164–23518Factor XI (%)50–15080–12782–14465–12318Factor XII (%)50–15078–12490–151129–19418Fibrinogen (mg/dL)233–496244–510291–538301–69618, 28, 29, 47, 51, 52, 62Fibronectin (mg/L)290 ± 85377 ± 309315 ± 295334 ± 25733Homocysteine (μmol/L)4.4–10.83.34–112.0–26.93.2–21.453, 56, 57, 64, 84International normalized ratio (INR)0.9–1.04g0.86–1.080.83–1.020.80–1.0917, 51Partial thromboplastin time, activated (aPTT) (sec)26.3–39.423.0–38.922.9–38.122.6–35.017, 18, 51, 52Prothrombin time (PT) (sec)12.7–15.49.7–13.59.5–13.49.6–12.918, 51, 52Protein C, functional (%)70–13078–12183–13367–13517, 27, 49Protein S, total (%)70–14039–10527–10133–10118, 27, 49Protein S, free (%)70–14034–13319–11320–6527, 49Protein S, functional activity (%)65–14057–9542–6816–4249Thrombin time (TT) (sec)17.7 ± 2.816.1 ± 1.515.4 ± 2.716.5 ± 2.433Thrombomodulin (ng/mL)2.7 ± 3.14.3 ± 1.34.2 ± 1.23.6 ± 1.333Tissue plasminogen activator (ng/mL)1.6–13h1.8–6.02.36–6.63.34–9.2017, 18, 29Tissue plasminogen activator inhibitor-1 (ng/mL)4–4316–3336–5567–9218, 29von Willebrand diseasevon Willebrand factor antigen (%)75–12562–31890–24784–42247, 55, 85ADAMTS-13, von Willebrand cleaving protease (%)40–170i40–16022–13538–10547, 55BLOOD CHEMICAL CONSTITUTENTSNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesAlanine aminotransferase (ALT) (U/L)7–413–302–332–256, 46, 52, 82Albumin (g/dL)4.1–5.3d3.1–5.12.6–4.52.3–4.23, 6, 30, 35, 46, 52, 84Alkaline phosphatase (U/L)33–9617–8825–12638–2293, 6, 46, 52, 82Alpha-1 antitrypsin (mg/dL)100–200225–323273–391327–48752Alpha-fetoprotein (ng/mL)——∼130–400∼130–59048Ammonia (μM)31 ± 3.2——27.3 ± 1.639Amylase (U/L)20–9624–8316–7315–8140, 46, 52, 80Anion gap (mmol/L)7–1613–1712–1612–1652Aspartate aminotransferase (AST) (U/L)12–383–233–334–326, 46, 52, 82Bicarbonate (mmol/L)22–3020–2420–2420–2452Bilirubin, total (mg/dL)0.3–1.30.1–0.40.1–0.80.1–1.16, 46Bilirubin, unconjugated (mg/dL)0.2–0.90.1–0.50.1–0.40.1–0.56, 52Bilirubin, conjugated (mg/dL)0.1–0.40–0.10–0.10–0.16Bile acids (μmol/L)0.3–4.8j0–4.90–9.10–11.36, 16CA-125 (μg/mL)7.2–272.2–26812–25.116.8–43.84, 37, 79Calcium, ionized (mg/dL)4.5–5.34.5–5.14.4–5.04.4–5.330, 52, 59, 67Calcium, total (mg/dL)8.7–10.28.8–10.68.2–9.08.2–9.73, 35, 46, 52, 59, 67, 74Ceruloplasmin (mg/dL)25–6330–4940–5343–7852, 54Chloride (mEq/L)102–109101–10597–10997–10922, 46, 52Creatinine (mg/dL)0.5–0.9d0.4–0.70.4–0.80.4–0.946, 52, 56Gamma-glutamyl transpeptidase (GGT) (U/L)9–582–234–223–266, 46, 52, 82Lactate dehydrogenase (U/L)115–22178–43380–44782–52435, 46, 52, 82Lipase (U/L)3–4321–7626–10041–11240Magnesium (mg/dL)1.5–2.31.6–2.21.5–2.21.1–2.23, 30, 35, 46, 52, 59, 74Osmolality (mOsm/kg H2O)275–295275–280276–289278–28019, 74Phosphate (mg/dL)2.5–4.33.1–4.62.5–4.62.8–4.63, 30, 41, 46, 52Potassium (mEq/L)3.5–5.03.6–5.03.3–5.03.3–5.122, 30, 35, 46, 52, 74, 77Prealbumin (mg/dL)17–3415–2720–2714–2352Protein, total (g/dL)6.7–8.66.2–7.65.7–6.95.6–6.730, 35, 52Sodium (mEq/L)136–146133–148129–148130–14819, 30, 35, 46, 52, 74, 77Urea nitrogen (mg/dL)7–207–123–133–1122, 46, 52Uric acid (mg/dL)2.5–5.6d2.0–4.22.4–4.93.1–6.319, 46, 52METABOLIC AND ENDOCRINE TESTSNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesAldosterone (ng/dL)2–96–1049–10415–10123, 42, 81Angiotensin-converting enzyme (ACE) (U/L)9–671–381–361–3922, 65Cortisol (μg/dL)0–257–1910–4212–5052, 81Hemoglobin A1C (%)4–64–64–64–759, 60, 70Parathyroid hormone (pg/mL)8–5110–1518–259–263Parathyroid hormone-related protein (pmol/L)<1.3e0.7–0.91.8–2.22.5–2.83Renin, plasma activity (ng/mL/hr)0.3–9.0eNot reported7.5–54.05.9–58.822, 42Thyroid stimulating hormone (TSH) (μIU/mL)0.34–4.250.60–3.400.37–3.600.38–4.0446, 52, 68Thyroxine-binding globulin (mg/dL)1.3–3.01.8–3.22.8–4.02.6–4.252Thyroxine, free (fT4) (ng/dL)0.8–1.70.8–1.20.6–1.00.5–0.852, 68Thyroxine, total (T4) (μg/dL)5.4–11.76.5–10.17.5–10.36.3–9.735, 52Triiodothyronine, free (fT3) (pg/mL)2.4–4.24.1–4.44.0–4.2Not reported68Triiodothyronine, total (T3) (ng/dL)77–13597–149117–169123–16252VITAMINS AND MINERALSNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesCopper (μg/dL)70–140112–199165–221130–2402, 36, 52Selenium (μg/L)63–160116–14675–14571–1332, 52Vitamin A (retinol) (μg/dL)20–10032–4735–4429–4252Vitamin B12 (pg/mL)279–966118–438130–65699–52656, 84Vitamin C (ascorbic acid) (mg/dL)0.4–1.0Not reportedNot reported0.9–1.375Vitamin D, 1,25-dihydroxy (pg/mL)25–4520–6572–16060–1193, 59Vitamin D, 24,25-dihydroxy (ng/mL)0.5–5.0e1.2–1.81.1–1.50.7–0.971Vitamin D, 25-hydroxy (ng/mL)14–8018–2710–2210–183, 71Vitamin E (α-tocopherol) (μg/mL)5–187–1310–1613–2352Zinc (μg/dL)75–12057–8851–8050–772, 52, 69AUTOIMMUNE AND INFLAMMATORY MEDIATORSNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesC3 complement (mg/dL)83–17762–9873–10377–11152C4 complement (mg/dL)16–4718–3618–3422–3252C-reactive protein (CRP) (mg/L)0.2–3.0Not reported0.4–20.30.4–8.134Erythrocyte sedimentation ... SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/03/28 UR - obgyn.mhmedical.com/content.aspx?aid=1190766848 ER -