TY - CHAP M1 - Book, Section TI - Neuraxial Morphine A1 - Colella, Merry I. A2 - Hess, Philip E. A2 - Li, Yunping A2 - Kowalczyk, John J. A2 - Stiles, Justin K. PY - 2023 T2 - Obstetric Anesthesia: Quick References & Practical Guides AB - Neuraxial morphine (intrathecal or epidural) has been used since the early 1980s to provide safe and effective postpartum postsurgical pain relief.1,2Respiratory depression associated with neuraxial morphine is extremely rare. It occurs with an average time of onset of 8 to 12 hours after neuraxial morphine installation.1Vigilant monitoring of the patient’s respiratory status for 24 hours after injection.Respiratory depression is most often associated with the use of supplemental narcotics or sedatives.For breastfeeding patients, the newborn is not appreciably affected by morphine excretion in the colostrum after neuraxial administration of morphine.Only administer neuraxial morphine when the postpartum floor has the capability to monitor the patients and monitoring policy is in place. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/03/29 UR - obgyn.mhmedical.com/content.aspx?aid=1199674205 ER -