TY - CHAP M1 - Book, Section TI - Hypotelorism A1 - Bianchi, Diana W. A1 - Crombleholme, Timothy M. A1 - D'Alton, Mary E. A1 - Malone, Fergal D. PY - 2015 T2 - Fetology: Diagnosis and Management of the Fetal Patient, 2e AB - Key PointsDefined as a decreased distance between the medial aspects of the orbital walls.Incidence is approximately 1 in 1220 livebirths.Main concern is its strong association with brain anomalies (especially holoprosencephaly).A fetal karyotype should be offered due to its association with aneuploidy, most commonly trisomy 13. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - obgyn.mhmedical.com/content.aspx?aid=1106397041 ER -