TY - CHAP M1 - Book, Section TI - Atrioventricular Canal Defect A1 - Bianchi, Diana W. A1 - Crombleholme, Timothy M. A1 - D'Alton, Mary E. A1 - Malone, Fergal D. PY - 2015 T2 - Fetology: Diagnosis and Management of the Fetal Patient, 2e AB - Key PointsAtrioventricular (AV) canal defect is the most common form of congenital heart disease detected prenatally and usually involves both a lower atrial and an upper ventricular septal defect, together with a common AV valve orifice.In 70% of cases there will be additional cardiac malformations, and in the majority of isolated cases additional chromosomal abnormality will be diagnosed, most commonly trisomy 21.Prenatal diagnosis of complete AV canal defect should be straightforward, by failure to visualize the normal crux on a four-chamber cardiac view.Management of pregnancy includes detailed echocardiographic and general fetal anatomic evaluation, amniocentesis, and planned delivery with complete pediatric cardiology backup.Overall prognosis is variable as prenatally diagnosed AV canal defects represent a heterogenous group. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - obgyn.mhmedical.com/content.aspx?aid=1106397910 ER -