TY - CHAP M1 - Book, Section TI - Coarctation of the Aorta A1 - Bianchi, Diana W. A1 - Crombleholme, Timothy M. A1 - D'Alton, Mary E. A1 - Malone, Fergal D. PY - 2015 T2 - Fetology: Diagnosis and Management of the Fetal Patient, 2e AB - Key PointsCoarctation of the aorta refers to a congenital narrowing of the aorta and is relatively common, accounting for 7% of cases of congenital heart disease.Prenatal diagnosis is generally possible following the discovery of asymmetry of the ventricles and outflow tracts.There is a strong association with chromosomal abnormalities, particularly Turner syndrome, as well as other cardiac and extracardiac malformations.Prenatal diagnosis is critical, as it leads to significantly improved neonatal morbidity and mortality.Following prenatal diagnosis, the infant should be delivered under controlled circumstances with prompt pediatric cardiology backup and the ability to start a prostaglandin infusion.Definitive therapy in infancy involves surgical correction by means of aortic resection and end-to-end anastomosis, although there is a growing role for catheter-based therapy with a combination of balloon dilation and stent placement. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - obgyn.mhmedical.com/content.aspx?aid=1106398153 ER -