TY - CHAP M1 - Book, Section TI - Intracardiac Tumors A1 - Bianchi, Diana W. A1 - Crombleholme, Timothy M. A1 - D'Alton, Mary E. A1 - Malone, Fergal D. PY - 2015 T2 - Fetology: Diagnosis and Management of the Fetal Patient, 2e AB - Key PointsIntracardiac tumors are extremely rare in fetuses, occurring in 0.11% to 0.14% of fetal echocardiographic studies.Most fetal intracardiac tumors (60%-80%) are due to rhabdomyoma. Other causes (in order of decreasing frequency) are teratoma, fibroma, vascular tumors, and myxoma. If multiple tumors are present, the diagnosis is almost always rhabdomyoma.Sixty to ninety-five percent of cases of rhabdomyoma are due to tuberous sclerosis, an autosomal dominant disorder.Antenatal management includes evaluation of fetal cardiac function and determining if dysrhythmias are present.Hydrops and dysrhythmias are associated with in utero demise. Overall, there is a 66% survival rate for fetuses with intracardiac tumors.Genetic consultation, examination of parents and siblings, fetal brain MRI, and level II sonography are all indicated to rule in or rule out tuberous sclerosis.Delivery should occur at a tertiary center.Most tumors regress postnatally, but if surgical removal is necessary, the postoperative prognosis is excellent.Tuberous sclerosis is associated with relatively high rates of new mutation and gonadal mosaicism, so the affected fetus/neonate should undergo DNA testing to both confirm diagnosis and provide a definitive means of prenatal diagnosis in future pregnancies. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - obgyn.mhmedical.com/content.aspx?aid=1106398479 ER -