TY - CHAP M1 - Book, Section TI - Liver Tumors A1 - Bianchi, Diana W. A1 - Crombleholme, Timothy M. A1 - D'Alton, Mary E. A1 - Malone, Fergal D. PY - 2015 T2 - Fetology: Diagnosis and Management of the Fetal Patient, 2e AB - Key PointsLiver tumors account for only 5% of fetal and neonatal tumors.The most common tumor is hemangioma followed by mesenchymal hamartoma and hepatoblastoma.Hemangiomas can be hypoechoic, hyperechoic, or undetectable and can result in high-output failure polyhydramnios and hydrops.Mesenchymal hamartomas tend to be cystic lesions.Hepatoblastomas are typically solid and echogenic and occasionally have calcifications.Hepatoblastoma can be associated with Beckwith–Wiedemann syndrome, familial adenomatous polyposis coli, and rarely, trisomy 18.Alpha-fetoprotein levels may be markedly elevated in mesenchymal hamartoma and neuroblastoma.In utero cyst decompression, rare mesenchymal hamartomas with extremely large cysts may be considered.Transplacental steroids may be helpful in large hemangiomas associated with high-output cardiac failure or hydrops.There is increased risk of intrauterine demise and stillbirth in primary hepatic tumors.Neonatal management of primary hepatic tumor is complicated and should be performed at centers with appropriate expertise. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - obgyn.mhmedical.com/content.aspx?aid=1106400918 ER -