TY  - CHAP
M1  - Book, Section
TI  - Disseminated Intravascular Coagulopathy
A1  - Clark, Steven L.
A2  - Pacheco, Luis D.
A2  - Saade, George R.
A2  - Hankins, Gary D.V.
PY  - 2015
T2  - Maternal Medicine
AB  - Disseminated  intravascular  coagulation  is  a  condition  in  which  the  normally  finely  tuned  balance  between  localized  clot  formation  and  clot  dissolution  becomes  disrupted  throughout  the  vascular  system.  This  may  result  in  pathologic  microvascular  thrombotic  obstruction  and  tissue  ischemia,  hemorrhage  due  to  consumption  of  available  clotting  factors,  or  both.  This  condition  may  be  encountered  in  a  wide  variety  of  clinical  situations.  However,  DIC  in  pregnancy  presents  the  clinician  with  special  challenges  due  to  profound  changes  in  the  baseline  system  of  coagulation  and  fibrinolysis,  the  presence  of  potent  thromboplastic  initiators  in  placental  tissue,  and  unique  clinical  considerations  when  dealing  with  a  mother-fetus  pair  and  the  process  of  childbirth.  This  chapter  will  examine  each  of  these  issues.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/16
UR  - obgyn.mhmedical.com/content.aspx?aid=1115521144
ER  -