RT Book, Section
A1 Ural, Serdar H.
A2 Silverman, Robert K.
SR Print(0)
ID 1139758435
T1 Pregestational and Gestational Diabetes
T2 Obesity Medicine: Management of Obesity in Women's Health Care
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9780071843515
LK obgyn.mhmedical.com/content.aspx?aid=1139758435
RD 2024/09/12
AB Pregestational  diabetes,  based  on  literature,  appears  to  be  present  in  approximately  1%  of  all  pregnancies.1  Type  1  diabetes  mellitus  tends  to  occur  early  in  human  life  and  appears  to  be  associated  with  an  autoimmune  disorder  that  alleviates  pancreatic  β  cells.  This  generally  leads  to  a  requirement  for  insulin  replacement.  Type  2  pregestational  diabetes  mellitus  is  associated  with  obesity,  insulin  deficiency,  insulin  resistance,  and  development  of  certain  complications,  such  as  neurologic,  renal,  and  vascular  issues.  Type  2  diabetes  has  increased  significantly  in  number  due  to  the  obesity  epidemic  in  the  United  States.2  Of  diabetic  cases  in  pregnancy,  90%  are  related  to  gestational  diabetes  mellitus.  Over  50%  of  such  patients  will  eventually  develop  type  2  pregestational  diabetes.  Obesity,  along  with  diabetes,  has  many  negative  consequences  during  pregnancy,  to  the  mother,  to  the  fetus,  to  the  newborn,  or  to  all.