RT Book, Section A1 Cunningham, F. Gary A1 Leveno, Kenneth J. A1 Bloom, Steven L. A1 Dashe, Jodi S. A1 Hoffman, Barbara L. A1 Casey, Brian M. A1 Spong, Catherine Y. SR Print(0) ID 1160782562 T1 Serum and Blood Constituents T2 Williams Obstetrics, 25e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259644320 LK obgyn.mhmedical.com/content.aspx?aid=1160782562 RD 2024/03/29 AB Table Graphic Jump LocationView Table||Download (.pdf)HEMATOLOGYNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesErythropoietinb (U/L)4–2712–258–6714–2227, 10, 47Ferritinb (ng/mL)10–150d6–1302–2300–1167, 10, 39, 42, 45, 47, 62, 70Folate, red blood cell (ng/mL)150–450137–58994–828109–66345, 46, 72Folate, serum (ng/mL)5.4–18.02.6–15.00.8–24.01.4–20.77, 43, 45, 46, 53, 58, 72Haptoglobin (mg/mL)25–250130 ± 43115 ± 50135 ± 6526AHemoglobinb (g/dL)12–15.8d11.6–13.99.7–14.89.5–15.010, 45, 47, 58, 62Hematocritb (%)35.4–44.431.0–41.030.0–39.028.0–40.06, 7, 10, 42, 4558, 66Iron, total binding capacity (TIBC)b (μg/dL)251–406278–403Not reported359–60962Iron, serumb (μg/dL)41–14172–14344–17830–19310, 62Mean corpuscular hemoglobin (MCH) (pg/cell)27–3230–3230–3329–3242Mean corpuscular volume (MCV) (×m3)79–9381–9682–9781–996, 42, 45, 58Platelet (×109/L)165–415174–391155–409146–4294, 6, 16, 42, 45Mean platelet volume (MPV) (μm3)6.4–11.07.7–10.37.8–10.28.2–10.442Red blood cell count (RBC) (×106/mm3)4.00–5.20d3.42–4.552.81–4.492.71–4.436, 42, 45, 58Red cell distribution width (RDW) (%)<14.512.5–14.113.4–13.612.7–15.342White blood cell count (WBC) (×103/mm3)3.5–9.15.7–13.65.6–14.85.9–16.96, 9, 42, 45, 58Neutrophils (×103/mm3)1.4–4.63.6–10.13.8–12.33.9–13.14, 6, 9, 42Lymphocytes (×103/mm3)0.7–4.61.1–3.60.9–3.91.0–3.64, 6, 9, 42Monocytes (×103/mm3)0.1–0.70.1–1.10.1–1.10.1–1.46, 9, 42Eosinophils (×103/mm3)0–0.60–0.60–0.60–0.66, 9Basophils (×103/mm3)0–0.20–0.10–0.10–0.16, 9Transferrin (mg/dL)200–400c254–344220–441288–53039, 42Transferrin, saturation without iron (%)22–46bNot reported10–445–3747Transferrin, saturation with iron (%)22–46bNot reported18–929–9847COAGULATIONNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesAntithrombin III, functional (%)70–13089–11478–12682–11615, 16, 39AD-Dimer (μg/mL)0.22–0.740.05–0.950.32–1.290.13–1.716, 25, 25C, 35, 39A, 41A, 51Factor V (%)50–15075–9572–9660–8840Factor VII (%)50–150100–14695–153149–211016Factor VIII (%)50–15090–21097–312143–35316, 40Factor IX (%)50–150103–172154–217164–23516Factor XI (%)50–15080–12782–14465–12316Factor XII (%)50–15078–12490–151129–19416Fibrinogen (mg/dL)233–496244–510291–538301–69616, 25, 25C, 39A, 41A, 42, 51Fibronectin (mg/L)290 ± 85377 ± 309315 ± 295334 ± 25727AHomocysteine (μmol/L)4.4–10.83.34–112.0–26.93.2–21.443, 45, 46, 53, 72International normalized ratio (INR)0.9–1.04g0.86–1.080.83–1.020.80–1.0915, 41APartial thromboplastin time, activated (aPTT) (sec)26.3–39.423.0–38.922.9–38.122.6–35.015, 16, 41A, 42Prothrombin time (PT) (sec)12.7–15.49.7–13.59.5–13.49.6–12.916, 41A, 42Protein C, functional (%)70–13078–12183–13367–13515, 24, 40Protein S, total (%)70–14039–10527–10133–10116, 24, 40Protein S, free (%)70–14034–13319–11320–6524, 40Protein S, functional activity (%)65–14057–9542–6816–4240Thrombin time (TT) (sec)17.7 ± 2.816.1 ± 1.515.4 ± 2.716.5 ± 2.427AThrombomodulin (ng/mL)2.7 ± 3.14.3 ± 1.34.2 ± 1.23.6 ± 1.327ATissue plasminogen activator (ng/mL)1.6–13h1.8–6.02.36–6.63.34–9.2015, 16, 25CTissue plasminogen activator inhibitor-1 (ng/mL)4–4316–3336–5567–9216, 25Cvon Willebrand disease von Willebrand factor antigen (%)75–12562–31890–24784–42239A, 44A, 73ADAMTS-13, von Willebrand cleaving protease (%)40–170i40–16022–13538–10539A, 44ABLOOD CHEMICAL CONSTITUTENTSNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesAlanine aminotransferase (ALT) (U/L)7–413–302–332–255, 39, 42, 70Albumin (g/dL)4.1–5.3d3.1–5.12.6–4.52.3–4.23, 5, 26, 29, 39, 42, 72Alkaline phosphatase (U/L)33–9617–8825–12638–2293, 5, 39, 42, 70Alpha-1 antitrypsin (mg/dL)100–200225–323273–391327–48742Alpha-fetoprotein (ng/mL)——∼130–400∼130–59039BAmmonia (μM)31 ± 3.2——27.3 ± 1.631AAmylase (U/L)20–9624–8316–7315–8132, 39, 42, 68Anion gap (mmol/L)7–1613–1712–1612–1642Aspartate aminotransferase (AST) (U/L)12–383–233–334–325, 39, 42, 70Bicarbonate (mmol/L)22–3020–2420–2420–2442Bilirubin, total (mg/dL)0.3–1.30.1–0.40.1–0.80.1–1.15, 39Bilirubin, unconjugated (mg/dL)0.2–0.90.1–0.50.1–0.40.1–0.55, 42Bilirubin, conjugated (mg/dL)0.1–0.40–0.10–0.10–0.15Bile acids (μmol/L)0.3–4.8j0–4.90–9.10–11.35, 14CA-125 (μg/mL)7.2–272.2–26812–25.116.8–43.83A, 30A, 67ACalcium, ionized (mg/dL)4.5–5.34.5–5.14.4–5.04.4–5.326, 42, 48, 56Calcium, total (mg/dL)8.7–10.28.8–10.68.2–9.08.2–9.73, 29, 39, 42, 48, 56, 63Ceruloplasmin (mg/dL)25–6330–4940–5343–7842, 44Chloride (mEq/L)102–109101–10597–10997–10920, 39, 42Creatinine (mg/dL)0.5–0.9d0.4–0.70.4–0.80.4–0.939, 42, 45Gamma-glutamyl transpeptidase (GGT) (U/L)9–582–234–223–265, 42, 39, 70Lactate dehydrogenase (U/L)115–22178–43380–44782–52442, 29, 39, 70Lipase (U/L)3–4321–7626–10041–11232Magnesium (mg/dL)1.5–2.31.6–2.21.5–2.21.1–2.23, 26, 29, 39, 42, 48, 63Osmolality (mOsm/kg H2O)275–295275–280276–289278–28017, 63Phosphate (mg/dL)2.5–4.33.1–4.62.5–4.62.8–4.63, 26, 33, 39, 42Potassium (mEq/L)3.5–5.03.6–5.03.3–5.03.3–5.120, 26, 29, 39, 42, 63, 66Prealbumin (mg/dL)17–3415–2720–2714–2342Protein, total (g/dL)6.7–8.66.2–7.65.7–6.95.6–6.726, 29, 42Sodium (mEq/L)136–146133–148129–148130–14817, 26, 29, 39, 42, 63, 66Urea nitrogen (mg/dL)7–207–123–133–1120, 39, 42Uric acid (mg/dL)2.5–5.6d2.0–4.22.4–4.93.1–6.317, 39, 42METABOLIC AND ENDOCRINE TESTSNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesAldosterone (ng/dL)2–96–1049–10415–10121, 34, 69Angiotensin-converting enzyme (ACE) (U/L)9–671–381–361–3920, 54Cortisol (μg/dL)0–257–1910–4212–5042, 69Hemoglobin A1C (%)4–64–64–64–748, 49, 59Parathyroid hormone (pg/mL)8–5110–1518–259–263Parathyroid hormone-related protein (pmol/L)<1.3e0.7–0.91.8–2.22.5–2.83Renin, plasma activity (ng/mL/hr)0.3–9.0eNot reported7.5–54.05.9–58.820, 34Thyroid stimulating hormone (TSH) (μIU/mL)0.34–4.250.60–3.400.37–3.600.38–4.0439, 42, 57Thyroxine-binding globulin (mg/dL)1.3–3.01.8–3.22.8–4.02.6–4.242Thyroxine, free (fT4) (ng/dL)0.8–1.70.8–1.20.6–1.00.5–0.842, 57Thyroxine, total (T4) (μg/dL)5.4–11.76.5–10.17.5–10.36.3–9.729, 42Triiodothyronine, free (fT3) (pg/mL)2.4–4.24.1–4.44.0–4.2Not reported57Triiodothyronine, total (T3) (ng/dL)77–13597–149117–169123–16242VITAMINS AND MINERALSNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesCopper (μg/dL)70–140112–199165–221130–2402, 30, 42Selenium (μg/L)63–160116–14675–14571–1332, 42Vitamin A (retinol) (μg/dL)20–10032–4735–4429–4242Vitamin B12 (pg/mL)279–966118–438130–65699–52645, 72Vitamin C (ascorbic acid) (mg/dL)0.4–1.0Not reportedNot reported0.9–1.364Vitamin D, 1,25-dihydroxy (pg/mL)25–4520–6572–16060–1193, 48Vitamin D, 24,25-dihydroxy (ng/mL)0.5–5.0e1.2–1.81.1–1.50.7–0.960Vitamin D, 25-hydroxy (ng/mL)14–8018–2710–2210–183, 60Vitamin E (α-tocopherol) (μg/mL)5–187–1310–1613–2342Zinc (μg/dL)75–12057–8851–8050–772, 42, 58AUTOIMMUNE AND INFLAMMATORY MEDIATORSNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesC3 complement (mg/dL)83–17762–9873–10377–11142C4 complement (mg/dL)16–4718–3618–3422–3242C-reactive protein (CRP) ...