RT Book, Section A1 Cunningham, F. Gary A1 Leveno, Kenneth J. A1 Bloom, Steven L. A1 Dashe, Jodi S. A1 Hoffman, Barbara L. A1 Casey, Brian M. A1 Spong, Catherine Y. SR Print(0) ID 1197209303 T1 Preterm Birth T2 Williams Obstetrics, 25e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259644320 LK obgyn.mhmedical.com/content.aspx?aid=1197209303 RD 2024/04/18 AB It is generally admitted that there exists in the medulla a centre for uterine contractions, which can be stimulated by an excess of carbon dioxide in the blood, by anaemia and the presence of various toxic substances; and it seems highly probable that the frequency of premature labour in cases of renal insufficiency and eclampsia may be due to the action of metabolic poisons upon the centre.—J. Whitridge Williams (1903)