RT Book, Section
A1 Pacheco, Luis D.
A1 Saade, George R.
A2 Foley, Michael R.
A2 Strong, Jr, Thomas H.
A2 Garite, Thomas J.
SR Print(0)
ID 1152536908
T1 Maternal Sepsis
T2 Obstetric Intensive Care Manual, 5e
YR 1
FD 1
PB McGraw-Hill Education
PP New York, NY
SN 9781259861758
LK obgyn.mhmedical.com/content.aspx?aid=1152536908
RD 2024/04/16
AB Sepsis  is  the  leading  cause  of  mortality  in  intensive  care  units  and  accounts  for  10%  of  direct  maternal  deaths  in  North  America.*  Most  deaths  in  sepsis  are  due  to  multiple  organ  dysfunction.  The  obstetric  patient  is  particularly  vulnerable  to  sepsis  because  of  the  association  between  pregnancy  and  infectious  complications  such  as  pyelonephritis,  chorioamnionitis,  endometritis,  wound  infection,  necrotizing  fasciitis,  and  cholecystitis.  Septic  shock  occurs  in  up  to  4%  of  bacteremic  patients,  and  40%  to  60%  of  patients  in  septic  shock  have  bacteremia.  The  relationship  between  bacteremia  and  sepsis  also  depends  on  other  contributing  factors,  such  as  immune  suppression,  and  associated  medical  conditions.  In  obstetrical  care,  sepsis  may  be  secondary  to  infections  from  viruses,  fungi,  gram-positive  bacteria,  gram-negative  bacteria,  and  anaerobes.  Importantly,  positive  cultures  are  not  required  to  establish  the  diagnosis  of  sepsis.