RT Book, Section A1 Hoffman, Barbara L. A1 Schorge, John O. A1 Halvorson, Lisa M. A1 Hamid, Cherine A. A1 Corton, Marlene M. A1 Schaffer, Joseph I. SR Print(0) ID 1171528733 T1 Abnormal Uterine Bleeding T2 Williams Gynecology, 4e YR 2020 FD 2020 PB McGraw-Hill Education PP New York, NY SN 9781260456868 LK obgyn.mhmedical.com/content.aspx?aid=1171528733 RD 2024/04/19 AB The endometrium is the source of most abnormal reproductive tract bleeding. It consists of two distinct zones, the functionalis layer and the basalis layer (Fig. 8-1). The basalis layer lies in direct contact with the myometrium and beneath the functionalis layer. The basalis serves as a reservoir for regeneration of the functionalis layer following menses. In contrast, the functionalis layer lines the uterine cavity and undergoes dramatic change throughout the menstrual cycle. It ultimately sloughs during menstruation. Histologically, the functionalis has a surface epithelium and underlying subepithelial capillary plexus. Beneath these are stroma, glands, and interspersed leukocytes (Fig. 33-1, p. 701).