RT Book, Section
A1 Cunningham, F. Gary
A1 Leveno, Kenneth J.
A1 Dashe, Jodi S.
A1 Hoffman, Barbara L.
A1 Spong, Catherine Y.
A1 Casey, Brian M.
SR Print(0)
ID 1190750137
T1 Teratology, Teratogens, and Fetotoxic Agents
T2 Williams Obstetrics, 26e
YR 2022
FD 2022
PB McGraw Hill
PP New York, NY
SN 9781260462739
LK obgyn.mhmedical.com/content.aspx?aid=1190750137
RD 2024/04/23
AB Birth  defects  are  common.  Of  all  newborns,  2  to  3  percent  have  a  major  congenital  abnormality  detectable  at  birth  (Cragan,  2009;  Dolk,  2010).  Some  medications  undoubtedly  pose  significant  risk  to  the  developing  embryo  or  fetus  (Table  8-1).  However,  80  percent  of  birth  defects  do  not  have  an  obvious  etiology,  and  of  those  with  an  identified  cause,  nearly  95  percent  of  cases  have  chromosomal  or  genetic  origins  (Feldkamp,  2017).  The  U.S.  Food  and  Drug  Administration  (FDA)  (2018)  estimates  that  <1  percent  of  all  birth  defects  are  caused  by  medications  (Fig.  8-1).