RT Book, Section A1 Cunningham, F. Gary A1 Leveno, Kenneth J. A1 Dashe, Jodi S. A1 Hoffman, Barbara L. A1 Spong, Catherine Y. A1 Casey, Brian M. SR Print(0) ID 1190766848 T1 Serum and Blood Constituents T2 Williams Obstetrics, 26e YR 2022 FD 2022 PB McGraw Hill PP New York, NY SN 9781260462739 LK obgyn.mhmedical.com/content.aspx?aid=1190766848 RD 2024/03/28 AB Table Graphic Jump LocationView Table||Download (.pdf)HEMATOLOGYNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesErythropoietinb (U/L)4–2712–258–6714–2228, 11, 58Ferritinb (ng/mL)10–150d6–1302–2300–1168, 11, 46, 52, 56,58, 73, 82Folate, red blood cell (ng/mL)150–450137–58994–828109–66356, 57, 84Folate, serum (ng/mL)5.4–18.02.6–15.00.8–24.01.4–20.78, 53, 56, 57,64, 69, 84Haptoglobin (mg/mL)25–250130 ± 43115 ± 50135 ± 6531Hemoglobinb (g/dL)12–15.8d11.6–13.99.7–14.89.5–15.011, 56, 58, 69, 73Hematocritb (%)35.4–44.431.0–41.030.0–39.028.0–40.07, 8, 11, 52, 5669, 77Iron, total binding capacity (TIBC)b (μg/dL)251–406278–403Not reported359–60973Iron, serumb (μg/dL)41–14172–14344–17830–19311, 73Mean corpuscular hemoglobin (MCH) (pg/cell)27–3230–3230–3329–3252Mean corpuscular volume (MCV) (×m3)79–9381–9682–9781–997, 52, 56, 69Platelet (×109/L)165–415174–391155–409146–4295, 7, 18, 52, 56Mean platelet volume (MPV) (μm3)6.4–11.07.7–10.37.8–10.28.2–10.452Red blood cell count (RBC) (×106/mm3)4.00–5.20d3.42–4.552.81–4.492.71–4.437, 52, 56, 69Red cell distribution width (RDW) (%)<14.512.5–14.113.4–13.612.7–15.352White blood cell count (WBC) (×103/mm3)3.5–9.15.7–13.65.6–14.85.9–16.97, 10, 52, 56, 69Neutrophils (×103/mm3)1.4–4.63.6–10.13.8–12.33.9–13.15, 7, 10, 52Lymphocytes (×103/mm3)0.7–4.61.1–3.60.9–3.91.0–3.65, 7, 10, 52Monocytes (×103/mm3)0.1–0.70.1–1.10.1–1.10.1–1.47, 10, 52Eosinophils (×103/mm3)0–0.60–0.60–0.60–0.67, 10Basophils (×103/mm3)0–0.20–0.10–0.10–0.17, 10Transferrin (mg/dL)200–400c254–344220–441288–53046, 52Transferrin, saturation without iron (%)22–46bNot reported10–445–3758Transferrin, saturation with iron (%)22–46bNot reported18–929–9858COAGULATIONNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesAntithrombin III, functional (%)70–13089–11478–12682–11617, 18, 47d-Dimer (μg/mL)0.22–0.740.05–0.950.32–1.290.13–1.718, 28, 29, 43, 47, 51, 62Factor V (%)50–15075–9572–9660–8849Factor VII (%)50–150100–14695–153149–211018Factor VIII (%)50–15090–21097–312143–35318, 49Factor IX (%)50–150103–172154–217164–23518Factor XI (%)50–15080–12782–14465–12318Factor XII (%)50–15078–12490–151129–19418Fibrinogen (mg/dL)233–496244–510291–538301–69618, 28, 29, 47, 51, 52, 62Fibronectin (mg/L)290 ± 85377 ± 309315 ± 295334 ± 25733Homocysteine (μmol/L)4.4–10.83.34–112.0–26.93.2–21.453, 56, 57, 64, 84International normalized ratio (INR)0.9–1.04g0.86–1.080.83–1.020.80–1.0917, 51Partial thromboplastin time, activated (aPTT) (sec)26.3–39.423.0–38.922.9–38.122.6–35.017, 18, 51, 52Prothrombin time (PT) (sec)12.7–15.49.7–13.59.5–13.49.6–12.918, 51, 52Protein C, functional (%)70–13078–12183–13367–13517, 27, 49Protein S, total (%)70–14039–10527–10133–10118, 27, 49Protein S, free (%)70–14034–13319–11320–6527, 49Protein S, functional activity (%)65–14057–9542–6816–4249Thrombin time (TT) (sec)17.7 ± 2.816.1 ± 1.515.4 ± 2.716.5 ± 2.433Thrombomodulin (ng/mL)2.7 ± 3.14.3 ± 1.34.2 ± 1.23.6 ± 1.333Tissue plasminogen activator (ng/mL)1.6–13h1.8–6.02.36–6.63.34–9.2017, 18, 29Tissue plasminogen activator inhibitor-1 (ng/mL)4–4316–3336–5567–9218, 29von Willebrand diseasevon Willebrand factor antigen (%)75–12562–31890–24784–42247, 55, 85ADAMTS-13, von Willebrand cleaving protease (%)40–170i40–16022–13538–10547, 55BLOOD CHEMICAL CONSTITUTENTSNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesAlanine aminotransferase (ALT) (U/L)7–413–302–332–256, 46, 52, 82Albumin (g/dL)4.1–5.3d3.1–5.12.6–4.52.3–4.23, 6, 30, 35, 46, 52, 84Alkaline phosphatase (U/L)33–9617–8825–12638–2293, 6, 46, 52, 82Alpha-1 antitrypsin (mg/dL)100–200225–323273–391327–48752Alpha-fetoprotein (ng/mL)——∼130–400∼130–59048Ammonia (μM)31 ± 3.2——27.3 ± 1.639Amylase (U/L)20–9624–8316–7315–8140, 46, 52, 80Anion gap (mmol/L)7–1613–1712–1612–1652Aspartate aminotransferase (AST) (U/L)12–383–233–334–326, 46, 52, 82Bicarbonate (mmol/L)22–3020–2420–2420–2452Bilirubin, total (mg/dL)0.3–1.30.1–0.40.1–0.80.1–1.16, 46Bilirubin, unconjugated (mg/dL)0.2–0.90.1–0.50.1–0.40.1–0.56, 52Bilirubin, conjugated (mg/dL)0.1–0.40–0.10–0.10–0.16Bile acids (μmol/L)0.3–4.8j0–4.90–9.10–11.36, 16CA-125 (μg/mL)7.2–272.2–26812–25.116.8–43.84, 37, 79Calcium, ionized (mg/dL)4.5–5.34.5–5.14.4–5.04.4–5.330, 52, 59, 67Calcium, total (mg/dL)8.7–10.28.8–10.68.2–9.08.2–9.73, 35, 46, 52, 59, 67, 74Ceruloplasmin (mg/dL)25–6330–4940–5343–7852, 54Chloride (mEq/L)102–109101–10597–10997–10922, 46, 52Creatinine (mg/dL)0.5–0.9d0.4–0.70.4–0.80.4–0.946, 52, 56Gamma-glutamyl transpeptidase (GGT) (U/L)9–582–234–223–266, 46, 52, 82Lactate dehydrogenase (U/L)115–22178–43380–44782–52435, 46, 52, 82Lipase (U/L)3–4321–7626–10041–11240Magnesium (mg/dL)1.5–2.31.6–2.21.5–2.21.1–2.23, 30, 35, 46, 52, 59, 74Osmolality (mOsm/kg H2O)275–295275–280276–289278–28019, 74Phosphate (mg/dL)2.5–4.33.1–4.62.5–4.62.8–4.63, 30, 41, 46, 52Potassium (mEq/L)3.5–5.03.6–5.03.3–5.03.3–5.122, 30, 35, 46, 52, 74, 77Prealbumin (mg/dL)17–3415–2720–2714–2352Protein, total (g/dL)6.7–8.66.2–7.65.7–6.95.6–6.730, 35, 52Sodium (mEq/L)136–146133–148129–148130–14819, 30, 35, 46, 52, 74, 77Urea nitrogen (mg/dL)7–207–123–133–1122, 46, 52Uric acid (mg/dL)2.5–5.6d2.0–4.22.4–4.93.1–6.319, 46, 52METABOLIC AND ENDOCRINE TESTSNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesAldosterone (ng/dL)2–96–1049–10415–10123, 42, 81Angiotensin-converting enzyme (ACE) (U/L)9–671–381–361–3922, 65Cortisol (μg/dL)0–257–1910–4212–5052, 81Hemoglobin A1C (%)4–64–64–64–759, 60, 70Parathyroid hormone (pg/mL)8–5110–1518–259–263Parathyroid hormone-related protein (pmol/L)<1.3e0.7–0.91.8–2.22.5–2.83Renin, plasma activity (ng/mL/hr)0.3–9.0eNot reported7.5–54.05.9–58.822, 42Thyroid stimulating hormone (TSH) (μIU/mL)0.34–4.250.60–3.400.37–3.600.38–4.0446, 52, 68Thyroxine-binding globulin (mg/dL)1.3–3.01.8–3.22.8–4.02.6–4.252Thyroxine, free (fT4) (ng/dL)0.8–1.70.8–1.20.6–1.00.5–0.852, 68Thyroxine, total (T4) (μg/dL)5.4–11.76.5–10.17.5–10.36.3–9.735, 52Triiodothyronine, free (fT3) (pg/mL)2.4–4.24.1–4.44.0–4.2Not reported68Triiodothyronine, total (T3) (ng/dL)77–13597–149117–169123–16252VITAMINS AND MINERALSNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesCopper (μg/dL)70–140112–199165–221130–2402, 36, 52Selenium (μg/L)63–160116–14675–14571–1332, 52Vitamin A (retinol) (μg/dL)20–10032–4735–4429–4252Vitamin B12 (pg/mL)279–966118–438130–65699–52656, 84Vitamin C (ascorbic acid) (mg/dL)0.4–1.0Not reportedNot reported0.9–1.375Vitamin D, 1,25-dihydroxy (pg/mL)25–4520–6572–16060–1193, 59Vitamin D, 24,25-dihydroxy (ng/mL)0.5–5.0e1.2–1.81.1–1.50.7–0.971Vitamin D, 25-hydroxy (ng/mL)14–8018–2710–2210–183, 71Vitamin E (α-tocopherol) (μg/mL)5–187–1310–1613–2352Zinc (μg/dL)75–12057–8851–8050–772, 52, 69AUTOIMMUNE AND INFLAMMATORY MEDIATORSNonpregnant Adulta1st Trimester2nd Trimester3rd TrimesterReferencesC3 complement (mg/dL)83–17762–9873–10377–11152C4 complement (mg/dL)16–4718–3618–3422–3252C-reactive protein (CRP) (mg/L)0.2–3.0Not reported0.4–20.30.4–8.134Erythrocyte sedimentation ...