RT Book, Section A1 Pilu, Gianluigi A1 Malinger, Gustavo A2 Malinger, Gustavo A2 Monteagudo, Ana A2 Pilu, Gianluigi A2 Paladini, Dario A2 Timor-Tritsch, Ilan E. SR Print(0) ID 1194695839 T1 Disorders of Prosencephalic Development: Holoprosencephaly T2 Timor's Ultrasonography of the Prenatal Brain, 4e YR 2023 FD 2023 PB McGraw Hill Education PP New York, NY SN 9781260136166 LK obgyn.mhmedical.com/content.aspx?aid=1194695839 RD 2024/04/25 AB KEY POINTSHoloprosencephaly derives from failed or incomplete cleavage of the prosencephalon and is featured by varying degrees of fusion of the cerebral hemispheres, and has a very severe prognosis in most cases.It is frequently associated with other anomalies and genetic conditions.Prenatal sonographic diagnosis of the most severe forms that typically are found with severe craniofacial malformations and is usually straightforward since early gestation.Lesser degrees of anatomic alteration are associated with more subtle findings that may be difficult to recognize or categorize.